SCHEMBL346302

SCHEMBL346302

COc1cccc(CCC(=O)O)c1

nearest known ligand 0.65

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 3/20 0.65
CYP1A2 P05177 1/20 0.60
PLA2G4A P47712 1/20 0.59
TAAR1 Q96RJ0 1/20 0.59
HDAC1 Q13547 1/20 0.58
HDAC6 Q9UBN7 1/20 0.58
RAB9A P51151 1/20 0.58
MTNR1A P48039 1/20 0.57
MTNR1B P49286 1/20 0.57
GAA P10253 1/20 0.56
LMNA P02545 1/20 0.56
CHRM2 P08172 1/20 0.56
CHRM1 P11229 1/20 0.56
CHRM3 P20309 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7758273 0.90 HDAC1 (0.63) FFAR1CYP1A2TAAR1HDAC1HDAC6
SCHEMBL29669893 0.90 HDAC1 (0.63) FFAR1CYP1A2TAAR1HDAC1HDAC6
Phenyl Propionic Acid SCHEMBL28549079 0.90 RAB9A (0.60) FFAR1CYP1A2PLA2G4AHDAC1HDAC6
SCHEMBL28188589 0.89 HDAC1 (0.70) CYP1A2TAAR1HDAC1HDAC6MTNR1A
SCHEMBL1206248 0.89 HDAC1 (0.70) CYP1A2TAAR1HDAC1HDAC6MTNR1A
Phenyl Propionic Acid SCHEMBL28910944 0.89 RAB9A (0.59) FFAR1CYP1A2PLA2G4AHDAC1HDAC6
SCHEMBL3463706 0.88 CYP1A2 (0.56) FFAR1CYP1A2PLA2G4ATAAR1HDAC1
SCHEMBL7332474 0.88 TAAR1 (0.61) TAAR1HDAC1HDAC6RAB9AMTNR1A
SCHEMBL25035334 0.87 HDAC1 (0.72) CYP1A2HDAC1HDAC6MTNR1AMTNR1B
SCHEMBL17274767 0.87 HDAC1 (0.72) CYP1A2HDAC1HDAC6MTNR1AMTNR1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4661890-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS Purdue Research Foundation (US) 2025-12-17 EP claimed
US-12497636-B2 Recombinant Saccharomyces cerevisiae cells for cannabinoid production NATIONAL UNIVERSITY OF SINGAPORE (SG) 2025-12-16 US claimed
US-12304894-B2 Derivatives of adamantyl oxadiazoles and pharmaceutically acceptable solvates, hydrates and salts thereof, pharmaceutical composition comprising same, synthesis method, suitable for use as effective and selective inhibitors of the reductase activity of the enzyme 11-beta dehydrogenase type 1 (11β-HSD1) PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (CL) 2025-05-20 US claimed
WO-2024167565-A1 PTP1B/TC-PTP DUAL INHIBITORS AND PROTEIN DEGRADERS PURDUE RESEARCH FOUNDATION (US) 2024-08-15 WO claimed
CN-118130691-A Method for detecting characteristic components of typical aroma in main stream smoke of cigarettes 上海烟草集团有限责任公司 2024-06-04 CN claimed
CN-117310059-B Plasma metabolism marker combination for early diagnosis or monitoring of Crohn disease and application thereof 中国人民解放军总医院 2024-02-02 CN claimed
CN-117310059-A Plasma metabolism marker combination for early diagnosis or monitoring of Crohn disease and application thereof 中国人民解放军总医院 2023-12-29 CN claimed
US-20220194909-A1 DERIVATIVES OF ADAMANTYL OXADIAZOLES AND PHARMACEUTICALLY ACCEPTABLE SOLVATES, HYDRATES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING SAME, SYNTHESIS METHOD, SUITABLE FOR USE AS EFFECTIVE AND SELECTIVE INHIBITORS OF THE REDUCTASE ACTIVITY OF THE ENZYME 11-BETA DEHYDROGENASE TYPE 1 (11B-HSD1) PONTIFICIA UNIVERSIDAD CATOLICA DE CHILE (CL) 2022-06-23 US claimed
WO-2020210922-A1 DERIVATIVES OF ADAMANTYL OXADIAZOLES AND PHARMACEUTICALLY ACCEPTABLE SOLVATES, HYDRATES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING SAME, SYNTHESIS METHOD, SUITABLE FOR USE AS EFFECTIVE AND SELECTIVE INHIBITORS OF THE REDUCTASE ACTIVITY OF THE ENZYME 11-BETA DEHYDROGENASE TYPE 1 (11Β-HSD1) PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE (CL) 2020-10-22 WO claimed
US-10072043-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2018-09-11 US claimed
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES Indiana University Research and Technology Corpora tion (US) 2016-06-23 US claimed
US-9217012-B2 Inhibitors of protein tyrosine phosphatases INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2015-12-22 US claimed
CN-102797043-B Medicinal molecular fragment library and construction process thereof Tianli (Tianjin) Technology Co., Ltd. (CN) 2015-11-25 CN claimed
CN-102797043-A Medicinal molecular fragment library and construction method thereof CBB NETWORK CO LTD 2012-11-28 CN claimed
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATI (US) 2012-04-12 US claimed
WO-2010118241-A2 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES INDIANA UNIVERSITY RESEARCH & TECHNOLOGY CORPORATION (US) 2010-10-14 WO claimed
CN-100497286-C Preparation method of 2,3-bihydrogen-1-indenone and its derivative WUHAN ZHONGXIN CHEMICAL CO LTD (CN) 2009-06-10 CN claimed
CN-1903818-A Preparation method of 2,3-bihydrogen-1-indenone and its derivative WUHAN ZHONGXIN CHEMICAL CO LTD (CN) 2007-01-31 CN claimed
CN-1029932-C Ingestibles containing substantially tasteless sweetness inhibitors as bitter taste reducers or substantially tasteless bitter inhibitors as sweet taste reducers BIORESEARCH INC (US) 1995-10-11 CN claimed
CN-1060770-A The sweetness inhibitor that contains substantially tasteless is as bitter inhibitor or contain the absorbed thing of the bitter inhibitor of substantially tasteless as sweetness inhibitor BIORESEARCH INC (US) 1992-05-06 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10072043-B2 Inhibitors of protein tyrosine phosphatases PTPRCAP, PTPRF, PTPRS FFAR1 4669/4885CYP1A2 4223/4885PLA2G4A 1572/4885
US-20220194909-A1 DERIVATIVES OF ADAMANTYL OXADIAZOLES AND PHARMACEUTICALLY ACCEPTABLE SOLVATES, HYDRATES AND SALTS THEREOF, PHARMACEUTICAL COMPOSITION COMPRISING SAME, SYNTHESIS METHOD, SUITABLE FOR USE AS EFFECTIVE AND SELECTIVE INHIBITORS OF THE REDUCTASE ACTIVITY OF THE ENZYME 11-BETA DEHYDROGENASE TYPE 1 (11B-HSD1) HSD11B1, HSD11B2, CYP11B1 FFAR1 695/4885CYP1A2 84/4885PLA2G4A 4335/4885
US-20160176922-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS FFAR1 4669/4885CYP1A2 4223/4885PLA2G4A 1572/4885
US-20120088720-A1 INHIBITORS OF PROTEIN TYROSINE PHOSPHATASES PTPRCAP, PTPRF, PTPRS FFAR1 4669/4885CYP1A2 4223/4885PLA2G4A 1572/4885
US-12304894-B2 Derivatives of adamantyl oxadiazoles and pharmaceutically acceptable solvates, hydrates and salts thereof, pharmaceutical composition comprising same, synthesis method, suitable for use as effective and selective inhibitors of the reductase activity of the enzyme 11-beta dehydrogenase type 1 (11β-HSD1) HSD11B1, HSD11B2, HSD17B1 FFAR1 623/4885CYP1A2 91/4885PLA2G4A 4316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.