SCHEMBL4619552

SCHEMBL4619552

Nc1cnc([N+](=O)[O-])c(OCc2ccccc2)c1

nearest known ligand 0.53

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.53
MEN1 O00255 2/20 0.53
MGMT P16455 1/20 0.47
CYP19A1 P11511 6/20 0.46
CYP11B1 P15538 3/20 0.46
CYP11B2 P19099 3/20 0.46
MAPT P10636 1/20 0.46
NPC1 O15118 3/20 0.45
RAB9A P51151 2/20 0.45
PIN1 Q13526 2/20 0.44
LTA4H P09960 1/20 0.43
MAPK14 Q16539 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23793998 0.83 KMT2A (0.53) KMT2AMEN1CYP19A1CYP11B1CYP11B2
SCHEMBL2338881 0.83 KMT2A (0.53) KMT2AMEN1CYP19A1CYP11B1CYP11B2
SCHEMBL28515689 0.81 KMT2A (0.51) KMT2AMEN1CYP19A1CYP11B1CYP11B2
SCHEMBL30892460 0.81 KMT2A (0.51) KMT2AMEN1CYP19A1CYP11B1CYP11B2
SCHEMBL29871300 0.81 KMT2A (0.51) KMT2AMEN1CYP19A1CYP11B1CYP11B2
SCHEMBL8568512 0.79 CA1 (0.41) KMT2AMEN1MGMTCYP19A1CYP11B1
SCHEMBL8567302 0.78 RAB9A (0.51) KMT2AMAPTRAB9A
SCHEMBL8568534 0.77 CYP19A1 (0.40) MGMTCYP19A1CYP11B1CYP11B2MAPT
SCHEMBL11422374 0.77 CYP19A1 (0.50) KMT2AMEN1MGMTCYP19A1CYP11B1
SCHEMBL30892469 0.77 KMT2A (0.63) KMT2AMEN1CYP19A1CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-7109260-A None JP disclosed
US-20080124732-A1 METHOD FOR OPTICAL MEASUREMENT OF MULTI-STRANDED NUCLEIC ACID FUJIFILM CORPORATION 2008-05-29 US disclosed
EP-1889880-A2 Method for optical measurement of multi-stranded nucleic acid FUJIFILM Corporation (JP) 2008-02-20 EP disclosed
EP-1362894-B1 Method for optical measurement of multi-stranded nucleic acid using cyanine dyes FUJIFILM CORP (JP) 2007-12-19 EP disclosed
US-20050112770-A1 Method for optical measurement of multi-stranded nucleic acid FUJI PHOTO FILM CO., LTD. 2005-05-26 US disclosed
EP-1362894-A2 Method for optical measurement of multi-stranded nucleic acid using cyanine dyes FUJI PHOTO FILM CO., LTD. (JP) 2003-11-19 EP disclosed
EP-0735025-B1 Process for producing aminonitropyridines SUMITOMO CHEMICAL CO (JP) 1998-07-01 EP disclosed
US-5648496-A AMINATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1997-07-15 US disclosed
EP-0735025-A1 Process for producing aminonitropyridines SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1996-10-02 EP disclosed
JP-H07109260-A PRODUCTION OF 5-AMINO-2-NITROPYRIDINE DERIVATIVE AND 5-DIAMOND-3-HYDROXYPYRIDINE DERIVATIVE FUJI PHOTO FILM CO LTD 1995-04-25 JP disclosed