Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4619552 | 0.77 | KMT2A (0.53) | CYP19A1CYP11B1CYP11B2MAPTMGMT | |
| SCHEMBL8569178 | 0.76 | ALDH1A1 (0.37) | MAPTHTTPOLBLMNA | |
| SCHEMBL8569474 | 0.76 | HTT (0.49) | MAPTHTTPOLBSMN1; SMN2LMNA | |
| SCHEMBL8561788 | 0.76 | ALDH1A1 (0.47) | MAPTPOLBSMN1; SMN2LMNANPC1 | |
| SCHEMBL7116983 | 0.75 | KMT2A (0.50) | CYP19A1CYP11B1CYP11B2MAPTSMN1; SMN2 | |
| SCHEMBL8559950 | 0.75 | ALDH1A1 (0.39) | MAPTHTTPOLBSMN1; SMN2LMNA | |
| SCHEMBL8562052 | 0.75 | ALDH1A1 (0.50) | MAPTHTTSMN1; SMN2LMNANPC1 | |
| SCHEMBL8566712 | 0.75 | CYP19A1 (0.43) | CYP19A1CYP11B1CYP11B2MAPTHTT | |
| SCHEMBL8596319 | 0.74 | ALDH1A1 (0.32) | MAPTHTTPOLB | |
| SCHEMBL8568330 | 0.73 | PIN1 (0.44) | CYP19A1CYP11B1CYP11B2MAPTPIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0735025-B1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL CO (JP) | 1998-07-01 | — | — | EP | disclosed |
| US-5648496-A | AMINATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0735025-A1 | Process for producing aminonitropyridines | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1996-10-02 | — | — | EP | disclosed |