SCHEMBL4619840

SCHEMBL4619840

Cc1cnc2nc(S)sc2c1

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.39
PSMD14 O00487 1/20 0.37
COPS5 Q92905 1/20 0.37
CCR1 P32246 2/20 0.36
CCR5 P51681 2/20 0.36
CCR8 P51685 2/20 0.36
AADAT Q8N5Z0 4/20 0.34
CYP1A2 P05177 1/20 0.33
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
HSD17B10 Q99714 1/20 0.31
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7912720 0.80 SMN1; SMN2 (0.43) KDM4ECCR1CCR5CCR8AADAT
SCHEMBL1761356 0.77 HRH3 (0.43) KDM4EHSD17B10MAPT
SCHEMBL7961498 0.77 HRH3 (0.43) MAPT
SCHEMBL1883423 0.77 KDM4E (0.39) KDM4ECCR1CCR5CCR8AADAT
SCHEMBL20489476 0.77 HSD17B10 (0.50) KDM4ECCR1CCR5CCR8CYP1A2
SCHEMBL23075881 0.74 KDM4E (0.37) KDM4EPSMD14COPS5CCR1CCR5
SCHEMBL13412399 0.74 ABL1 (0.38) KDM4ECCR1CCR5CCR8AADAT
SCHEMBL4619864 0.74 SMN1; SMN2 (0.40) KDM4ECCR1CCR5CCR8AADAT
SCHEMBL22333711 0.69 SMN1; SMN2 (0.41) HSD17B10MAPTRAB9A
SCHEMBL1771426 0.67 RAB9A (0.61) KDM4EMAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080124732-A1 METHOD FOR OPTICAL MEASUREMENT OF MULTI-STRANDED NUCLEIC ACID FUJIFILM CORPORATION 2008-05-29 US disclosed
EP-1889880-A2 Method for optical measurement of multi-stranded nucleic acid FUJIFILM Corporation (JP) 2008-02-20 EP disclosed
EP-1362894-B1 Method for optical measurement of multi-stranded nucleic acid using cyanine dyes FUJIFILM CORP (JP) 2007-12-19 EP disclosed
US-20050112770-A1 Method for optical measurement of multi-stranded nucleic acid FUJI PHOTO FILM CO., LTD. 2005-05-26 US disclosed
EP-1362894-A2 Method for optical measurement of multi-stranded nucleic acid using cyanine dyes FUJI PHOTO FILM CO., LTD. (JP) 2003-11-19 EP disclosed