Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 16/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 15/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL457488 | 0.80 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL459381 | 0.78 | SLC6A4 (0.41) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL456972 | 0.72 | GPR119 (0.53) | — | |
| SCHEMBL458214 | 0.71 | PLAT (0.34) | SLC6A4SLC6A2SLC6A3MAOAMAOB | |
| SCHEMBL1679711 | 0.70 | GPR119 (0.57) | SLC6A4SLC6A2SLC6A3KCNH2 | |
| SCHEMBL634422 | 0.68 | SLC6A2 (0.57) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL634421 | 0.68 | SLC6A2 (0.57) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL634424 | 0.68 | SLC6A2 (0.57) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL635037 | 0.68 | SLC6A2 (0.57) | SLC6A4SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL635036 | 0.68 | SLC6A2 (0.57) | SLC6A4SLC6A2SLC6A3CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |