Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAT | P00750 | 3/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | GPR183 | P32249 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL459381 | 0.73 | SLC6A4 (0.41) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL1679711 | 0.73 | GPR119 (0.57) | SLC6A2SLC6A4SLC6A3GPR119GPR183 | |
| SCHEMBL457488 | 0.71 | SLC6A4 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL461993 | 0.71 | SLC6A4 (0.37) | SLC6A2SLC6A4SLC6A3MAOAMAOB | |
| SCHEMBL470596 | 0.68 | ALDH1A1 (0.46) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL384915 | 0.66 | GPR119 (0.59) | GPR119GPR183 | |
| SCHEMBL386891 | 0.66 | GPR119 (0.59) | GPR119GPR183 | |
| SCHEMBL1673933 | 0.65 | NR1H4 (0.47) | PLATGPR119MAOAMAOB | |
| SCHEMBL38665029 | 0.64 | KDM1A (0.40) | PLATGPR119MAOAMAOB | |
| Hydrochloric Acid SCHEMBL514637 | 0.64 | NR1H4 (0.46) | PLATGPR119MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |