SCHEMBL4619944

SCHEMBL4619944

N#CCCc1c[c]ccc1

nearest known ligand 0.57

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
MMP9 P14780 1/20 0.31
MMP13 P45452 1/20 0.31
EGFR P00533 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10349761 0.86 MEN1 (0.42) MEN1KMT2A
SCHEMBL17133916 0.82 MEN1 (0.36) MEN1KMT2A
SCHEMBL1560823 0.78
SCHEMBL159206 0.76 MAOA (0.44)
SCHEMBL13618845 0.75 MEN1 (0.70) MEN1KMT2A
SCHEMBL28037506 0.75 MEN1 (0.62) MEN1KMT2AMMP9MMP13
SCHEMBL181108 0.75 MEN1 (0.70) MEN1KMT2A
SCHEMBL242001 0.75 MEN1 (0.56) MEN1KMT2AMMP9MMP13EGFR
Benzene SCHEMBL28469748 0.75 MEN1 (0.70) MEN1KMT2A
SCHEMBL27636919 0.75 MAOB (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1622610-B1 1-(2H-PYRAZOL-3-YL)-3-{4-[1-(BENZOYL)-PIPERIDIN-4-YLMETHYL]-PHENYL}-UREA DERIVATIVES AND RELATED COMPOUNDS AS INHIBITORS OF P38 KINASE AND/OR TNF INHIBITORS FOR THE TREATMENT OF INFLAMMATIONS AVENTIS PHARMA INC (US) 2006-12-20 EP claimed
EP-4107151-A1 HETEROARYL-TRIAZOLE COMPOUNDS AS PESTICIDES Bayer Aktiengesellschaft (DE) 2022-12-28 EP disclosed
CN-106057722-B Film for flip chip type semiconductor back surface and dicing tape-integrated film for semiconductor back surface 日东电工株式会社 2019-03-08 CN disclosed
CN-105355975-B electrolyte and lithium ion battery including the electrolyte 宁德新能源科技有限公司 2018-08-21 CN disclosed
CN-105261789-B electrolyte and lithium ion battery including the electrolyte 宁德新能源科技有限公司 2018-07-27 CN disclosed
US-20180108947-A9 ELECTROLYTE AND LITHIUM-ION BATTERY CONTAINING THE SAME NINGDE AMPEREX TECHNOLOGY LTD. (CN) 2018-04-19 US disclosed
CN-107887320-A Film for flip chip type semiconductor back surface and dicing tape-integrated film for semiconductor back surface 日东电工株式会社 2018-04-06 CN disclosed
CN-105070947-B Electrolyte and the lithium ion battery including the electrolyte 宁德新能源科技有限公司 2017-07-14 CN disclosed
US-20170084956-A1 ELECTROLYTE AND LITHIUM-ION BATTERY CONTAINING THE SAME Amperex Technology Limited (CN) 2017-03-23 US disclosed
CN-105355975-A Electrolyte solution and lithium ion battery comprising same NINGDE AMPEREX TECHNOLOGY LTD 2016-02-24 CN disclosed
CN-102906198-A Curable composition, cured product, and method for using curable composition LINTEC CORP 2013-01-30 CN disclosed
EP-1893605-A2 SAMINOPYRIMIDINE DERIVATES WITH TIE2 INHIBITING ACTIVITY AstraZeneca AB (SE) 2008-03-05 EP disclosed
EP-1863805-A1 PYRIMIDINE COMPOUNDS HAVING TIE2 (TEK) INHIBITORY ACTIVITY AstraZeneca AB (SE) 2007-12-12 EP disclosed
EP-1848715-A1 COMPOUNDS HAVING TIE2 (TEK) INHIBITORY ACTIVITY AstraZeneca AB (SE) 2007-10-31 EP disclosed
EP-1846399-A1 PYRIMIDINE COMPOUNDS HAVING TIE2 (TEK) INHIBITORY ACTIVITY AstraZeneca AB (SE) 2007-10-24 EP disclosed
WO-2006103449-A2 SAMINOPYRIMIDINE DERIVATES WITH TIE2 INHIBITING ACTIVITY ASTRAZENECA AB (SE) 2006-10-05 WO disclosed
WO-2006082373-A1 PYRIMIDINE COMPOUNDS HAVING TIES (TEK) INHIBITORY ACTIVITY ASTRAZENECA AB (SE) 2006-08-10 WO disclosed
WO-2006082404-A1 COMPOUNDS HAVING TIE2 (TEK) INHIBITORY ACTIVITY ASTRAZENECA AB (SE) 2006-08-10 WO disclosed
WO-2006082371-A1 PYRIMIDINE COMPOUNDS HAVING TIE2 (TEK) INHIBITORY ACTIVITY ASTRAZENECA AB (SE) 2006-08-10 WO disclosed
EP-0411423-A2 Curable dielectric polyphenylene ether-polyepoxide compositions GENERAL ELECTRIC COMPANY (US) 1991-02-06 EP disclosed