Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.56 |
| ▸ | CLTC | Q00610 | 1/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29895481 | 1.00 | RECQL (0.59) | RECQLSCN2AMEN1KMT2ACA12 | |
| SCHEMBL9807393 | 0.82 | CA12 (0.64) | RECQLSCN2AMEN1KMT2ACA12 | |
| SCHEMBL5924422 | 0.82 | SCN2A (0.58) | RECQLSCN2AMEN1KMT2ACA12 | |
| SCHEMBL11864526 | 0.82 | CYP3A4 (0.59) | RECQLSCN2AMEN1KMT2ACA12 | |
| SCHEMBL10885870 | 0.82 | RECQL (0.59) | RECQLSCN2AMEN1KMT2ACA12 | |
| SCHEMBL9113889 | 0.80 | CA12 (0.72) | RECQLSCN2AMEN1KMT2ACA12 | |
| SCHEMBL18806465 | 0.79 | RECQL (0.62) | RECQLSCN2AMEN1KMT2ACA12 | |
| SCHEMBL30758606 | 0.78 | RECQL (0.62) | RECQLSCN2AMEN1KMT2ACA12 | |
| SCHEMBL16592564 | 0.78 | RECQL (0.62) | RECQLSCN2AMEN1KMT2ACA12 | |
| SCHEMBL9240516 | 0.78 | CYP3A4 (0.66) | SCN2AMEN1KMT2ANR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115124452-B | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2024-03-01 | — | — | CN | claimed |
| CN-115124452-A | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2022-09-30 | — | — | CN | claimed |
| CN-110724086-A | Synthetic method of pyrroltinib intermediate | 山东铂源药业有限公司 | 2020-01-24 | — | — | CN | claimed |
| CN-115124452-B | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-115124452-B | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2024-03-01 | — | — | CN | disclosed |
| CN-115124452-A | Preparation method of 2- (4-amino-2-ethoxyphenyl) isoindole-1, 3-dione | 安庆朗坤药业有限公司 | 2022-09-30 | — | — | CN | disclosed |
| CN-110724086-A | Synthetic method of pyrroltinib intermediate | 山东铂源药业有限公司 | 2020-01-24 | — | — | CN | disclosed |
| CN-110724086-A | Synthetic method of pyrroltinib intermediate | 山东铂源药业有限公司 | 2020-01-24 | — | — | CN | disclosed |
| EP-1883621-A2 | METHODS OF PREPARING 3-CYANO-QUINOLINES AND INTERMEDIATES MADE THEREBY | Wyeth (US) | 2008-02-06 | — | — | EP | disclosed |
| US-20060270669-A1 | Method of preparing 3-cyano-quinolines and intermediates made thereby | WYETH | 2006-11-30 | — | — | US | disclosed |
| WO-2006127205-A2 | METHODS OF PREPARING 3-CYANO-QUINOLINES AND INTERMEDIATES MADE THEREBY | WYETH (US) | 2006-11-30 | — | — | WO | disclosed |
| US-4873338-A | Process for the preparation of 2-amino-5-acylamino phenols and starting compounds suitable therefor | AGFA-GEVAERT AKTIENGESELLSCHAFT (DE) | 1989-10-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270669-A1 | Method of preparing 3-cyano-quinolines and intermediates made thereby | CNP, PPP4C, PTMS | RECQL 199/4885SCN2A 546/4885MEN1 2418/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.