Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN2A | Q99250 | 2/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | S100A4 | P26447 | 1/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620082 | 0.82 | RECQL (0.59) | SCN2ARECQLKMT2AALDH1A1NR1H2 | |
| SCHEMBL10885870 | 0.82 | RECQL (0.59) | SCN2ARECQLKMT2AALDH1A1NR1H2 | |
| SCHEMBL29895481 | 0.82 | RECQL (0.59) | SCN2ARECQLKMT2AALDH1A1NR1H2 | |
| SCHEMBL11864526 | 0.82 | CYP3A4 (0.59) | SCN2ARECQLKMT2AALDH1A1NR1H2 | |
| SCHEMBL5924386 | 0.81 | SCN2A (0.57) | SCN2ARECQLKMT2ANR1H2NR1H3 | |
| SCHEMBL9113889 | 0.80 | CA12 (0.72) | SCN2ARECQLKMT2AALDH1A1NR1H2 | |
| SCHEMBL18806465 | 0.79 | RECQL (0.62) | SCN2ARECQLKMT2AALDH1A1NR1H2 | |
| SCHEMBL16592564 | 0.78 | RECQL (0.62) | SCN2ARECQLKMT2AALDH1A1NR1H2 | |
| SCHEMBL30758606 | 0.78 | RECQL (0.62) | SCN2ARECQLKMT2AALDH1A1NR1H2 | |
| SCHEMBL5653191 | 0.78 | ALDH1A1 (0.64) | KMT2AALDH1A1MEN1CTDSP1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270628-A1 | Antiinfective 1,2,3-triazole derivatives, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES, INC. | 2006-11-30 | — | — | US | disclosed |
| WO-2004101531-A1 | ANTIINFECTIVE 1,2,3-TRIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2004-11-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270628-A1 | Antiinfective 1,2,3-triazole derivatives, process for their preparation and pharmaceutical compositions containing them | IL33, IL5, IL1B | SCN2A 3732/4885RECQL 2001/4885KMT2A 4744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.