SCHEMBL4620113

SCHEMBL4620113

CCCCCCCCCCCCCCCCOc1cccc(C(C)([SiH2]O)c2cccc(OCCCCCCCCCCCCCCCC)c2)c1

nearest known ligand 0.54

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.54
CYP2D6 P10635 1/20 0.49
CACNA1B Q00975 1/20 0.49
GGPS1 O95749 2/20 0.49
SMPD1 P17405 3/20 0.49
PLA2G4B P0C869 3/20 0.47
CYSLTR2 Q9NS75 3/20 0.45
CYSLTR1 Q9Y271 3/20 0.45
THRA P10827 1/20 0.45
THRB P10828 1/20 0.45
LMNA P02545 1/20 0.45
POLB P06746 1/20 0.45
HTT P42858 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
NR5A1 Q13285 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4619825 0.84 TSHR (0.52) TSHRCYP2D6CACNA1BGGPS1SMPD1
SCHEMBL4619594 0.82 NR5A1 (0.57) TSHRPLA2G4BLMNANR5A1
SCHEMBL20267505 0.82 L3MBTL1 (0.58) TSHRCYP2D6CACNA1BGGPS1SMPD1
SCHEMBL10778564 0.79 L3MBTL1 (0.62) TSHRCYP2D6CACNA1BGGPS1SMPD1
SCHEMBL17138169 0.78 TSHR (0.76) TSHRGGPS1SMPD1PLA2G4BCYSLTR2
SCHEMBL6677146 0.78 TSHR (0.76) TSHRGGPS1SMPD1PLA2G4BCYSLTR2
SCHEMBL16699620 0.78 TSHR (0.76) TSHRGGPS1SMPD1PLA2G4BCYSLTR2
SCHEMBL4208924 0.78 TSHR (0.76) TSHRGGPS1SMPD1PLA2G4BCYSLTR2
SCHEMBL3905859 0.78 TSHR (0.76) TSHRGGPS1SMPD1PLA2G4BCYSLTR2
SCHEMBL17138159 0.78 TSHR (0.76) TSHRGGPS1SMPD1PLA2G4BCYSLTR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1889862-A1 Curable resin composition, process for producing the same, and coated object made with the same DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2008-02-20 EP disclosed
EP-1172393-B1 CURABLE RESIN COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND COATED OBJECT MADE WITH THE SAME DAICEL CHEM (JP) 2007-10-31 EP disclosed
US-6924008-B2 Curable resin composition, a method for the preparation thereof, and a coated article thereof DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2005-08-02 US disclosed
US-20030032729-A1 Curable resin composition, process for producing the same, and coated object made with the same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-02-13 US disclosed
EP-1172393-A1 CURABLE RESIN COMPOSITION, PROCESS FOR PRODUCING THE SAME, AND COATED OBJECT MADE WITH THE SAME DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) 2002-01-16 EP disclosed