Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.55 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.40 |
| ▸ | APLNR | P35414 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30178662 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP2C19L3MBTL1ERN1 | |
| SCHEMBL11173 | 0.81 | ALDH1A1 (0.63) | ALDH1A1CYP1A2CYP2C19L3MBTL1ERN1 | |
| SCHEMBL10075194 | 0.81 | MEN1 (0.45) | ALDH1A1MAOBMEN1KMT2ACYP1A2 | |
| SCHEMBL15981210 | 0.81 | MAOB (0.47) | ALDH1A1MAOBMEN1KMT2ACYP1A2 | |
| SCHEMBL19839152 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TUBB1MAOBL3MBTL1ERN1 | |
| SCHEMBL29724497 | 0.79 | ALDH1A1 (0.51) | ALDH1A1TUBB1MAOBL3MBTL1ERN1 | |
| SCHEMBL16199144 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2ACYP1A2CYP3A4 | |
| SCHEMBL6232985 | 0.76 | PARP10 (0.62) | ALDH1A1TUBB1MAOBMEN1KMT2A | |
| SCHEMBL5885604 | 0.76 | ALDH1A1 (0.68) | ALDH1A1TUBB1MAOBMEN1KMT2A | |
| SCHEMBL31001958 | 0.76 | HDAC8 (0.54) | ALDH1A1TUBB1MAOBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8871893-B2 | Signal-responsive plastics | THE PENN STATE RESEARCH FOUNDATION (US) | 2014-10-28 | — | — | US | disclosed |
| US-20140242623-A1 | SIGNAL-RESPONSIVE PLASTICS | THE PENN STATE RESEARCH FOUNDATION | 2014-08-28 | — | — | US | disclosed |
| WO-2012005806-A2 | SIGNAL-RESPONSIVE PLASTICS | THE PENN STATE RESEARCH FOUNDATION (US) | 2012-01-12 | — | — | WO | disclosed |