Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.34 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3836011 | 0.97 | NR1H4 (0.34) | CTSDNR1H4 | |
| SCHEMBL4664295 | 0.96 | NR1H4 (0.37) | CTSDNR1H4 | |
| SCHEMBL4596808 | 0.94 | NR1H4 (0.36) | CTSDNR1H4 | |
| SCHEMBL3834127 | 0.93 | NR1H4 (0.38) | CTSDNR1H4 | |
| SCHEMBL14895745 | 0.93 | NR1H4 (0.33) | CTSDNR1H4 | |
| SCHEMBL5709136 | 0.92 | NR1H4 (0.35) | CTSDNR1H4 | |
| SCHEMBL6157024 | 0.90 | NR1H4 (0.34) | CTSDNR1H4 | |
| SCHEMBL5709156 | 0.89 | CTSD (0.33) | CTSDNR1H4 | |
| SCHEMBL4617149 | 0.89 | NR1H4 (0.35) | CTSDNR1H4 | |
| SCHEMBL14895557 | 0.89 | NR1H4 (0.42) | CTSDNR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885694-A2 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | Microbia, Inc. (US) | 2008-02-13 | — | — | EP | disclosed |
| EP-1851197-A2 | PHENYLAZETIDINONE DERIVATIVES | Microbia, Inc. (US) | 2007-11-07 | — | — | EP | disclosed |
| WO-2006124713-A2 | 4-BIARYLYL-1-PHENYLAZETIDIN-2-ONES | MICROBIA, INC. (US) | 2006-11-23 | — | — | WO | disclosed |
| WO-2006086562-A2 | PHENYLAZETIDINONE DERIVATIVES | MICROBIA, INC. (US) | 2006-08-17 | — | — | WO | disclosed |
| EP-1572626-A1 | THERAPEUTIC AGENTS | Astrazeneca AB (SE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056748-A1 | THERAPEUTIC AGENTS | ASTRAZENECA AB (SE) | 2004-07-08 | — | — | WO | disclosed |