SCHEMBL4620770

SCHEMBL4620770

CCCc1cc(C(O)(CC)CC)ccc1-c1cc(OCc2ccc(CO)c(C(O)I)c2)ccc1C

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
VDR P11473 3/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2641441 0.88 VDR (0.84) VDR
SCHEMBL4881104 0.86 VDR (0.77) VDR
SCHEMBL27568064 0.82 VDR (0.51) VDR
SCHEMBL2890000 0.81 VDR (0.66) VDR
SCHEMBL6564164 0.81 VDR (0.77) VDR
SCHEMBL6566698 0.80 VDR (0.62) VDR
SCHEMBL229168 0.80 VDR (1.00) VDR
SCHEMBL6564192 0.79 VDR (0.68) VDR
SCHEMBL2639763 0.78 VDR (0.67) VDR
SCHEMBL4888601 0.78 VDR (0.92) VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1885374-A2 PHARMACEUTICAL COMPOSITION COMPRISING AN OLEAGINOUS OINTMENT AND VITAMIN D OR THE DERIVATIVES THEREOF IN SOLUBILISED FORM Galderma Research & Development (FR) 2008-02-13 EP claimed
WO-2006123031-A2 PHARMACEUTICAL COMPOSITION COMPRISING AN OLEAGINOUS OINTMENT AND VITAMIN D OR THE DERIVATIVES THEREOF IN SOLUBILISED FORM GALDERMA RESEARCH & DEVELOPMENT (FR) 2006-11-23 WO claimed
EP-1885374-A2 PHARMACEUTICAL COMPOSITION COMPRISING AN OLEAGINOUS OINTMENT AND VITAMIN D OR THE DERIVATIVES THEREOF IN SOLUBILISED FORM Galderma Research & Development (FR) 2008-02-13 EP disclosed
WO-2006123031-A2 PHARMACEUTICAL COMPOSITION COMPRISING AN OLEAGINOUS OINTMENT AND VITAMIN D OR THE DERIVATIVES THEREOF IN SOLUBILISED FORM GALDERMA RESEARCH & DEVELOPMENT (FR) 2006-11-23 WO disclosed