Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 3/20 | 0.43 |
| ▸ | MMP1 | P03956 | 2/20 | 0.43 |
| ▸ | MMP7 | P09237 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621468 | 1.00 | ADAMTS4 (0.53) | ADAMTS4HTTMMP2MMP9MMP3 | |
| SCHEMBL4620791 | 1.00 | ADAMTS4 (0.53) | ADAMTS4HTTMMP2MMP9MMP3 | |
| SCHEMBL4622173 | 0.82 | CA1 (0.47) | HTTMMP2MMP9MMP3MMP13 | |
| SCHEMBL4621268 | 0.82 | CA1 (0.47) | HTTMMP2MMP9MMP3MMP13 | |
| SCHEMBL4620575 | 0.82 | CA1 (0.47) | HTTMMP2MMP9MMP3MMP13 | |
| SCHEMBL4618978 | 0.81 | PARP1 (0.51) | MMP2MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL4621066 | 0.81 | PARP1 (0.51) | MMP2MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL4622849 | 0.81 | PARP1 (0.51) | MMP2MAPTSMN1; SMN2POLBKMT2A | |
| SCHEMBL4619909 | 0.77 | HPGD (0.49) | ADAMTS4HTTCA2CA1XBP1 | |
| SCHEMBL4622868 | 0.77 | HPGD (0.49) | ADAMTS4HTTCA2CA1XBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |