Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4620411 | 0.89 | PPARA (0.33) | PPARAMAPTSENP7CASP3SENP8 | |
| SCHEMBL4620002 | 0.86 | PPARA (0.36) | PPARASENP7CASP3SENP8SENP6 | |
| SCHEMBL4623108 | 0.85 | HTT (0.34) | PPARAMAPK1 | |
| SCHEMBL4621178 | 0.84 | PPARA (0.31) | PPARA | |
| SCHEMBL4620378 | 0.83 | PPARA (0.33) | PPARAMAPTSENP7CASP3SENP8 | |
| SCHEMBL4092707 | 0.79 | MAPT (0.33) | MAPTSENP7CASP3SENP8SENP6 | |
| SCHEMBL4622103 | 0.77 | LMNA (0.35) | PPARAMAPTSENP7CASP3SENP8 | |
| SCHEMBL4619193 | 0.76 | LMNA (0.34) | PPARAMAPTSENP7CASP3SENP8 | |
| SCHEMBL4618747 | 0.76 | LMNA (0.34) | PPARAMAPTSENP7CASP3SENP8 | |
| SCHEMBL4085450 | 0.75 | KDM4E (0.36) | MAPTMAPK1SENP7CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1897880-A1 | 1,3-BENZOTHIAZINONE DERIVATIVE AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2008-03-12 | — | — | EP | disclosed |