Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.54 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 3/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.40 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621022 | 1.00 | PRMT5 (0.54) | PRMT5WDR77STAT3CTDSP1SIRT5 | |
| SCHEMBL2967503 | 0.84 | ALDH1A1 (0.50) | PRMT5WDR77ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL14762196 | 0.84 | ALDH1A1 (0.50) | PRMT5WDR77ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL8898161 | 0.84 | ALDH1A1 (0.50) | PRMT5WDR77ALDH1A1CYP3A4ALOX15 | |
| SCHEMBL9645456 | 0.77 | PRMT5 (0.72) | PRMT5WDR77PKMALDH1A1LMNA | |
| SCHEMBL1164097 | 0.77 | PRMT5 (0.72) | PRMT5WDR77PKMALDH1A1LMNA | |
| SCHEMBL2967442 | 0.77 | PRMT5 (0.72) | PRMT5WDR77PKMALDH1A1LMNA | |
| SCHEMBL439063 | 0.75 | PRMT5 (0.54) | PRMT5WDR77STAT3PKMALDH1A1 | |
| SCHEMBL450879 | 0.75 | PRMT5 (0.54) | PRMT5WDR77STAT3PKMALDH1A1 | |
| SCHEMBL439062 | 0.75 | PRMT5 (0.54) | PRMT5WDR77STAT3PKMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885849-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE GLYCIDYL ETHERS AND OPTICALLY ACTIVE VICINAL DIOLS FROM RACEMIC SUBSTRATES | Oxyrane UK Limited (GB) | 2008-02-13 | — | — | EP | disclosed |
| WO-2006109198-A2 | METHODS FOR OBTAINING OPTICALLY ACTIVE GLYCIDYL ETHERS AND OPTICALLY ACTIVE VICINAL DIOLS FROM RACEMIC SUBSTRATES | OXYRANE UK LIMITED (GB) | 2006-10-19 | — | — | WO | disclosed |