Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.72 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 8/20 | 0.43 |
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA9 | Q16790 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.43 |
| ▸ | CA7 | P43166 | 4/20 | 0.43 |
| ▸ | CA3 | P07451 | 3/20 | 0.43 |
| ▸ | CA4 | P22748 | 3/20 | 0.43 |
| ▸ | CA6 | P23280 | 3/20 | 0.43 |
| ▸ | CA5A | P35218 | 3/20 | 0.43 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9645456 | 1.00 | PRMT5 (0.72) | PRMT5WDR77PKMALDH1A1LMNA | |
| SCHEMBL1164097 | 1.00 | PRMT5 (0.72) | PRMT5WDR77PKMALDH1A1LMNA | |
| SCHEMBL30301224 | 0.84 | PRMT5 (1.00) | PRMT5WDR77ALDH1A1LMNAGAA | |
| SCHEMBL336605 | 0.84 | PRMT5 (1.00) | PRMT5WDR77ALDH1A1LMNAGAA | |
| SCHEMBL336603 | 0.84 | PRMT5 (1.00) | PRMT5WDR77ALDH1A1LMNAGAA | |
| SCHEMBL29481767 | 0.84 | PRMT5 (1.00) | PRMT5WDR77ALDH1A1LMNAGAA | |
| SCHEMBL449928 | 0.84 | PRMT5 (1.00) | PRMT5WDR77ALDH1A1LMNAGAA | |
| SCHEMBL29476299 | 0.84 | PRMT5 (1.00) | PRMT5WDR77ALDH1A1LMNAGAA | |
| SCHEMBL9303799 | 0.83 | PRMT5 (0.53) | PRMT5WDR77PKMALDH1A1CA2 | |
| SCHEMBL7470093 | 0.83 | PRMT5 (0.67) | PRMT5WDR77PKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119708491-A | Polydisulfide polymer material containing hydroxy ester group and preparation method thereof | 衢州化工新材料创新研究院 | 2025-03-28 | — | — | CN | claimed |
| WO-2014140220-A1 | PROCESS FOR THE PREPARATION OF (2,3-DIHYDRO-BENZO[B][1,4]DIOXIN-2-YL) METHANOL DERIVATIVES | JANSSEN PHARMACEUTICA, N.V. (BE) | 2014-09-18 | — | — | WO | claimed |
| CN-119708491-A | Polydisulfide polymer material containing hydroxy ester group and preparation method thereof | 衢州化工新材料创新研究院 | 2025-03-28 | — | — | CN | disclosed |
| CN-117242073-A | PRMT5 inhibitors and uses thereof | 海思科医药集团股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| WO-2022206964-A1 | PRMT5 INHIBITOR AND USE THEREOF | 海思科医药集团股份有限公司 | 2022-10-06 | — | — | WO | disclosed |
| CN-107226797-B | A kind of chipal compounds 2, the preparation method of 2- dimethyl -3- (ethylene oxide -2- base) methyl propionate | 沈阳金久奇科技有限公司 | 2019-05-17 | — | — | CN | disclosed |
| WO-2016071382-A1 | SYNTHESIS OF PI3K INHIBITOR AND SALTS THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-05-12 | — | — | WO | disclosed |
| EP-1973917-B1 | PROTEIN KINASE INHIBITORS | ABBVIE INC (US) | 2015-06-10 | — | — | EP | disclosed |
| US-8552188-B2 | Epoxy compound and method for manufacturing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | disclosed |
| US-20130072683-A1 | EPOXY COMPOUND AND METHOD FOR MANUFACTURING THE SAME | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-03-21 | — | — | US | disclosed |
| US-8344148-B2 | Epoxy compound and method for manufacturing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-01-01 | — | — | US | disclosed |
| US-6087512-A | Process for preparation of glycidyl ether | DAISO CO., LTD. (JP) | 2000-07-11 | — | — | US | disclosed |
| US-6057476-A | Process for the preparation of 3-amino-2-hydroxy-1-propyl ethers | DAISO CO., LTD. (JP) | 2000-05-02 | — | — | US | disclosed |
| EP-0930291-A1 | PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXY-1-PROPYL ETHERS | DAISO CO., LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |
| EP-0930307-A1 | PROCESS FOR THE PREPARATION OF GLYCIDYL ETHERS | DAISO CO., LTD. (JP) | 1999-07-21 | — | — | EP | disclosed |
| CN-1160714-A | Process for stereoselective preparation of hetero-bicyclic alcohol enantiomer | DUPHAR INT RES (NL) | 1997-10-01 | — | — | CN | disclosed |
| EP-0786459-A1 | Process for the preparation of a hetero-bicyclic alcohol enantiomer | DUPHAR INTERNATIONAL RESEARCH B.V (NL) | 1997-07-30 | — | — | EP | disclosed |
| EP-0609025-B1 | Process for producing optically active epoxy alcohol derivatives | ARCO CHEM TECH (US) | 1996-04-17 | — | — | EP | disclosed |
| EP-0609025-A1 | Process for producing optically active epoxy alcohol derivatives | ARCO Chemical Technology, L.P. (US) | 1994-08-03 | — | — | EP | disclosed |
| US-4877892-A | Chiral glycidyl azides as synthetic intermediates to optically active compounds | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1989-10-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130072683-A1 | EPOXY COMPOUND AND METHOD FOR MANUFACTURING THE SAME | SQLE, CYP2E1, CYP1A1 | PRMT5 393/4885WDR77 343/4885PKM 1495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.