Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | MMP12 | P39900 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MMP1 | P03956 | 1/20 | 0.51 |
| ▸ | MMP7 | P09237 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ACLY | P53396 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621599 | 1.00 | MMP8 (0.51) | MMP8MMP12MMP13TSHRKMT2A | |
| SCHEMBL4619221 | 1.00 | MMP8 (0.51) | MMP8MMP12MMP13TSHRKMT2A | |
| SCHEMBL8095873 | 0.86 | MEN1 (0.45) | MMP8MMP12MMP13TSHRKMT2A | |
| SCHEMBL4620781 | 0.84 | MMP8 (0.56) | MMP8MMP12MMP13KMT2AMEN1 | |
| SCHEMBL4621111 | 0.84 | MMP8 (0.56) | MMP8MMP12MMP13KMT2AMEN1 | |
| SCHEMBL4620227 | 0.84 | MMP8 (0.56) | MMP8MMP12MMP13KMT2AMEN1 | |
| SCHEMBL7475872 | 0.83 | SLC1A3 (0.60) | MMP8MMP12MMP13TSHRKMT2A | |
| SCHEMBL18697078 | 0.83 | SLC1A3 (0.60) | MMP8MMP12MMP13TSHRKMT2A | |
| SCHEMBL7462670 | 0.83 | SLC1A3 (0.60) | MMP8MMP12MMP13TSHRKMT2A | |
| SCHEMBL10879503 | 0.83 | IDO1 (0.54) | MMP8MMP12MMP13KMT2AMMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1884230-A1 | PARAKERATOSIS INHIBITOR, PORE-SHRINKING AGENT OR AGENT FOR PREVENTING/AMELIORATING ROUGH SKIN AND EXTERNAL COMPOSITION FOR SKIN | Shiseido Company, Limited (JP) | 2008-02-06 | — | — | EP | disclosed |