Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP7 | P09237 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4621065 | 0.86 | MMP8 (0.51) | MEN1TSHRKMT2AADAMTS4HTT | |
| SCHEMBL4621599 | 0.86 | MMP8 (0.51) | MEN1TSHRKMT2AADAMTS4HTT | |
| SCHEMBL4619221 | 0.86 | MMP8 (0.51) | MEN1TSHRKMT2AADAMTS4HTT | |
| SCHEMBL27375585 | 0.82 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C9CYP2C19ABCB11 | |
| SCHEMBL8653921 | 0.77 | MMP1 (0.40) | ALDH1A1ABCB11HPGDMMP1MMP7 | |
| SCHEMBL7475872 | 0.76 | SLC1A3 (0.60) | MEN1TSHRKMT2AADAMTS4HTT | |
| SCHEMBL18697078 | 0.76 | SLC1A3 (0.60) | MEN1TSHRKMT2AADAMTS4HTT | |
| SCHEMBL7462670 | 0.76 | SLC1A3 (0.60) | MEN1TSHRKMT2AADAMTS4HTT | |
| SCHEMBL8101285 | 0.76 | MMP12 (0.61) | ABCB11MMP1MMP7MMP8MMP12 | |
| SCHEMBL8657587 | 0.76 | MMP8 (0.51) | MEN1KMT2AALDH1A1ABCB11HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080869-A | Benzothiazolone derivatives | ASTRA PHARMACEUTICALS LIMITED (GB) | 2000-06-27 | — | — | US | disclosed |