Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TBXA2R | P21731 | 10/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.39 |
| ▸ | FLT4 | P35916 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6105235 | 0.84 | CDK1 (0.82) | CDK1GAAMAPT | |
| SCHEMBL6105199 | 0.84 | CDK1 (0.72) | CDK1GAAALDH1A1MAPT | |
| SCHEMBL13043135 | 0.83 | CDK1 (0.80) | CDK1GAAMAPT | |
| SCHEMBL10509250 | 0.83 | CDK1 (0.70) | CDK1GAAKDM4EALDH1A1MAPT | |
| SCHEMBL7924847 | 0.82 | CDK1 (0.70) | CDK1GAAMAPT | |
| SCHEMBL6106106 | 0.82 | CDK1 (0.79) | CDK1GAAALDH1A1MAPT | |
| SCHEMBL1652674 | 0.82 | CDK1 (0.76) | CDK1GAAKDM4EALDH1A1MAPT | |
| SCHEMBL28551087 | 0.82 | CDK1 (0.79) | CDK1GAAMAPT | |
| SCHEMBL2977298 | 0.82 | CDK1 (0.79) | CDK1GAAMAPT | |
| SCHEMBL5847825 | 0.82 | CDK1 (0.78) | CDK1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106349168-A | Preparation method of foramsulfuron intermediate of sulfonylurea herbicide | 淮安国瑞化工有限公司 | 2017-01-25 | — | — | CN | disclosed |
| EP-1097144-B1 | METHOD FOR PRODUCING 4,6-DISUBSTITUTED 2-ISOCYANATOPYRIMIDINES AND THEIR USE AS INTERMEDIATE PRODUCTS FOR ACTIVE INGREDIENT SYNTHESES | BAYER CROPSCIENCE AG (DE) | 2008-03-19 | — | — | EP | disclosed |
| US-7057043-B2 | Processes for preparing aminophenylsulfonylureas, and intermediates therefor | HOECHST SCHERING AGREVO GMBH (DE) | 2006-06-06 | — | — | US | disclosed |
| US-20050033047-A1 | Processes for preparing aminophenylsulfonylureas, and intermediates therefor | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2005-02-10 | — | — | US | disclosed |
| US-6790955-B2 | REACTING 2-SULFONAMIDO, NITROBENZOIC ACID COMPOUND WITH IN THE PRESENCE OF A HALOGENATING AGENT, WITH FORMATION OF THE CARBONYL HALIDE AND ITS REARRANGEMENT; AMMONOLYSIS AT SO2CL GROUP REDUCING AT THE NITRO GROUP; REACTING WITH CARBAMATE | HOECHST SCHERING AGREVO GMBH (DE) | 2004-09-14 | — | — | US | disclosed |
| US-20030096991-A1 | Processes for the preparation of aminophenylsulfonyl-ureas and intermediate products for the processes | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2003-05-22 | — | — | US | disclosed |
| US-6500952-B1 | SUCH AS 5-AMINO-2-DIMETHYLAMINOCARBONYL-N-((4,6-DIMETHOXY-PYRIMIDIN-2-YL) -AMINOCARBONYL)BENZENESULFONAMIDE; HERBICIDES OR PLANT GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 2002-12-31 | — | — | US | disclosed |
| US-6365739-B1 | REACTION OF AMINOPYRAMIDINE WITH PHOSGENE TO FORM ISOCYANATO PYRIMIDINE | HOECHST SCHERING AGREVO GMBH (DE) | 2002-04-02 | — | — | US | disclosed |
| EP-0858447-B1 | METHODS OF PRODUCING AMINOPHENYLSULPHONYL CARBAMIDES AND INTERMEDIATE PRODUCTS FOR USE IN THE PROCESS | AVENTIS CROPSCIENCE GMBH (DE) | 2002-01-09 | — | — | EP | disclosed |
| EP-1097144-A1 | METHOD FOR PRODUCING 4,6-DISUBSTITUTED 2-ISOCYANATOPYRIMIDINES AND TO THEIR USE AS INTERMEDIATE PRODUCTS FOR ACTIVE INGREDIENT SYNTHESES | Aventis CropScience GmbH (DE) | 2001-05-09 | — | — | EP | disclosed |
| WO-2000005220-A1 | METHOD FOR PRODUCING 4,6-DISUBSTITUTED 2-ISOCYANATOPYRIMIDINES AND TO THEIR USE AS INTERMEDIATE PRODUCTS FOR ACTIVE INGREDIENT SYNTHESES | AVENTIS CROPSCIENCE GMBH (DE) | 2000-02-03 | — | — | WO | disclosed |
| EP-0858447-A1 | METHODS OF PRODUCING AMINOPHENYLSULPHONYL CARBAMIDES AND INTERMEDIATE PRODUCTS FOR USE IN THE PROCESS | Hoechst Schering AgrEvo GmbH (DE) | 1998-08-19 | — | — | EP | disclosed |
| WO-1997016419-A1 | METHODS OF PRODUCING AMINOPHENYLSULPHONYL CARBAMIDES AND INTERMEDIATE PRODUCTS FOR USE IN THE PROCESS | HOECHST SCHERING AGREVO GMBH (DE) | 1997-05-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033047-A1 | Processes for preparing aminophenylsulfonylureas, and intermediates therefor | HNMT, PRMT3, CBR3 | CDK1 505/4885GAA 4676/4885TBXA2R 1772/4885 |
| US-20030096991-A1 | Processes for the preparation of aminophenylsulfonyl-ureas and intermediate products for the processes | HNMT, CPS1, HRH4 | CDK1 298/4885GAA 3678/4885TBXA2R 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.