SCHEMBL19347607

SCHEMBL19347607

CCCCCN(C)c1nc2c(N)nc3ccccc3c2n1CC(C)C.CCCCN(C)c1nc2c(N)nc3ccccc3c2n1CC(C)C.CCCCNc1nc2c(N)nc3ccccc3c2n1CC(C)C.CCCNc1nc2c(N)nc3ccccc3c2n1CC(C)C

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 20/20 0.43
TLR8 Q9NR97 12/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4556287 0.98 TLR7 (0.42) TLR7TLR8
SCHEMBL25338771 0.98 TLR7 (0.42) TLR7TLR8
SCHEMBL3275133 0.94 TLR7 (0.41) TLR7TLR8
SCHEMBL4238527 0.92 TLR7 (0.45) TLR7TLR8
SCHEMBL4621585 0.91 TLR7 (0.41) TLR7TLR8
SCHEMBL143656 0.89 TLR7 (0.52) TLR7TLR8
SCHEMBL4019917 0.89 TLR7 (0.50) TLR7TLR8
SCHEMBL147063 0.88 TLR7 (0.51) TLR7TLR8
SCHEMBL31092872 0.88 TLR7 (0.51) TLR7TLR8
SCHEMBL149093 0.87 TLR7 (0.52) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230357369-A1 RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2023-11-09 US disclosed
EP-4159232-A1 RSV IMMUNIZATION REGIMEN GlaxoSmithKline Biologicals S.A. (BE) 2023-04-05 EP disclosed
EP-4144368-A1 RSV IMMUNIZATION REGIMEN GlaxoSmithKline Biologicals S.A. (BE) 2023-03-08 EP disclosed
US-20190275141-A1 RSV IMMUNIZATION REGIMEN GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) 2019-09-12 US disclosed
US-10342862-B2 RSV immunization regimen GLAXOSMITHKLINE BIOLOGICALS, SA (BE) 2019-07-09 US disclosed
EP-2707385-B1 PRE-FUSION RSV F ANTIGENS GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2017-09-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357369-A1 RSV F PROTEIN COMPOSITIONS AND METHODS FOR MAKING SAME RNASEL, TIMCC, RNGTT TLR7 349/4885TLR8 1489/4885
US-10342862-B2 RSV immunization regimen IL5, IL15, IFNG TLR7 48/4885TLR8 77/4885
US-20190275141-A1 RSV IMMUNIZATION REGIMEN IL5, IL15, IFNG TLR7 48/4885TLR8 77/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.