Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TBXA2R | P21731 | 6/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALB | P02768 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MCOLN2 | Q8IZK6 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | MCOLN1 | Q9GZU1 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2690134 | 0.78 | TSHR (0.50) | TSHRALDH1A1LMNAMAPTHTT | |
| SCHEMBL4624018 | 0.74 | TSHR (0.59) | TSHRALDH1A1LMNAHTTCYP3A4 | |
| SCHEMBL28669648 | 0.74 | ALDH1A1 (0.59) | TSHRALDH1A1LMNAMAPTHTT | |
| SCHEMBL3970619 | 0.72 | ALDH1A1 (0.72) | TSHRALDH1A1LMNAMAPTHTT | |
| SCHEMBL30613684 | 0.71 | MMP2 (0.64) | TSHRALDH1A1LMNACYP3A4POLB | |
| SCHEMBL8068632 | 0.71 | MMP2 (0.64) | TSHRALDH1A1LMNACYP3A4POLB | |
| SCHEMBL21751533 | 0.71 | MMP2 (0.64) | TSHRALDH1A1LMNACYP3A4POLB | |
| SCHEMBL21751532 | 0.71 | MMP2 (0.64) | TSHRALDH1A1LMNACYP3A4POLB | |
| SCHEMBL1612364 | 0.71 | MCHR1 (0.39) | TSHRALDH1A1LMNACYP2C9ALB | |
| SCHEMBL17481681 | 0.71 | TSHR (0.61) | TSHRALDH1A1LMNAHTTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008039367-A1 | SYNTHESIS OF TRANS-TERT-BUTYL-2-AMINOCYCLOPENTYLCARBAMATE | THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2008-04-03 | — | — | WO | claimed |