Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.41 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.41 |
| ▸ | RIMKLA | Q8IXN7 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2247729 | 0.93 | ALDH1A1 (0.43) | FOLH1NAALAD2RIMKLALMNABLM | |
| SCHEMBL2254202 | 0.91 | ALDH1A1 (0.46) | FOLH1NAALAD2RIMKLALMNABLM | |
| SCHEMBL2244920 | 0.91 | ALDH1A1 (0.46) | FOLH1NAALAD2RIMKLALMNABLM | |
| SCHEMBL10935612 | 0.85 | FOLH1 (0.53) | FOLH1NAALAD2RIMKLAEPHX2GGH | |
| SCHEMBL10935609 | 0.85 | FOLH1 (0.53) | FOLH1NAALAD2RIMKLAEPHX2GGH | |
| SCHEMBL2252360 | 0.78 | HPGDS (0.41) | NAALAD2HPGDSCYP1A2GRM7GGH | |
| SCHEMBL4621861 | 0.78 | KMT2A (0.44) | FOLH1NAALAD2RIMKLALMNABLM | |
| SCHEMBL5323996 | 0.78 | KMT2A (0.44) | FOLH1NAALAD2RIMKLALMNABLM | |
| SCHEMBL29501687 | 0.76 | EPHX2 (0.53) | FOLH1NAALAD2RIMKLALMNAEPHX2 | |
| SCHEMBL2249643 | 0.75 | TDP1 (0.41) | FOLH1NAALAD2RIMKLALMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1902014-A2 | GLUTAMATE AGGRECANASE INHIBITORS | Wyeth (US) | 2008-03-26 | — | — | EP | disclosed |
| WO-2007008994-A2 | GLUTAMATE AGGRECANASE INHIBITORS | WYETH (US) | 2007-01-18 | — | — | WO | disclosed |