Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Deanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GGT1 | P19440 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Deanol SCHEMBL8040658 | 0.90 | MEN1 (0.39) | FFAR3LMNAMEN1KMT2AGGT1 | |
| Deanol SCHEMBL11871103 | 0.88 | MEN1 (0.37) | LMNAMEN1KMT2AGGT1ALDH1A1 | |
| Deanol SCHEMBL16685376 | 0.85 | MEN1 (0.35) | LMNAMEN1KMT2AGGT1ALDH1A1 | |
| Acetic Acid SCHEMBL22346335 | 0.85 | FFAR3 (0.41) | FFAR3LCKFYNLMNAMEN1 | |
| Deanol SCHEMBL28335877 | 0.84 | LMNA (0.40) | LMNAMEN1KMT2AGGT1ALDH1A1 | |
| Methacrylic Acid SCHEMBL11265929 | 0.84 | TDP1 (0.39) | LMNAMEN1KMT2AGGT1KDM4E | |
| Deanol SCHEMBL609 | 0.83 | — | — | |
| Deanol SCHEMBL27486030 | 0.83 | MEN1 (0.50) | LMNAMEN1KMT2AALDH1A1TSHR | |
| Deanol SCHEMBL4621611 | 0.82 | FFAR3 (0.56) | FFAR3LMNAMEN1KMT2AGGT1 | |
| Deanol SCHEMBL7564579 | 0.82 | CA1 (0.44) | LMNAMEN1KMT2AGRM4BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102299322-A | Ion hot preparation method for lithium iron phosphate positive electrode material | — | 2011-12-28 | — | — | CN | claimed |
| CN-102299325-A | Ionothermal process of manganese lithium phosphate anode material | — | 2011-12-28 | — | — | CN | claimed |
| CN-102299325-B | Ionothermal process of manganese lithium phosphate anode material | UNIV HEFEI TECHNOLOGY | 2015-02-04 | — | — | CN | disclosed |
| CN-102299322-B | Ion hot preparation method for lithium iron phosphate positive electrode material | UNIV HEFEI TECHNOLOGY | 2014-12-03 | — | — | CN | disclosed |
| US-8648120-B2 | Liquid rheology modifier | KAO CORPORATION (JP) | 2014-02-11 | — | — | US | disclosed |
| CN-102299322-A | Ion hot preparation method for lithium iron phosphate positive electrode material | — | 2011-12-28 | — | — | CN | disclosed |
| CN-102299325-A | Ionothermal process of manganese lithium phosphate anode material | — | 2011-12-28 | — | — | CN | disclosed |
| US-20080078814-A1 | Liquid rheology modifier | KAO CORPORATION (JP) | 2008-04-03 | — | — | US | disclosed |
| EP-1897927-A2 | Liquid rheology modifier | Kao Corporation (JP) | 2008-03-12 | — | — | EP | disclosed |
| US-6235464-B1 | DETECTING VIRAL ANTIGEN IN LIQUID; MIXING VIRUS CONTAINING LIQUID WITH COATED MEMBRANES, SEPARATE MEMBRANE FROM LIQUID, INCUBATE MEMBRANE WITH TRACER, INCUBATE WITH A SECOND LIQUID CONTAINING SUBSTRATE FOR TRACER, DETECT VIRAL ANTIGEN | HENDERSON GLENN L (US) | 2001-05-22 | — | — | US | disclosed |
| EP-0633472-B1 | Immunoassay on a preblocked solid surface | BECTON DICKINSON CO (US) | 2000-05-17 | — | — | EP | disclosed |
| EP-0633472-A2 | Immunoassay on a preblocked solid surface | Becton, Dickinson and Company (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5208143-A | Immunoassay on a preblocked solid surface | BECTON, DICKINSON AND COMPANY (US) | 1993-05-04 | — | — | US | disclosed |
| US-5135847-A | Levamisole as phosphatase inhibitor; immunoassay | BECTON, DICKINSON AND COMPANY (US) | 1992-08-04 | — | — | US | disclosed |
| US-5093231-A | Levamisole | BECTON, DICKINSON AND COMPANY (US) | 1992-03-03 | — | — | US | disclosed |
| EP-0369361-A2 | Immunoassay on a preblocked solid surface | Becton, Dickinson and Company (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0369362-A2 | Substrate composition for alkaline phosphatase and method for assay using same | Becton, Dickinson and Company (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0347256-A2 | Method for detecting a substance in a sample | TOSOH CORPORATION (JP) | 1989-12-20 | — | — | EP | disclosed |
| US-4053329-A | METHOD OF IMPROVING CORROSION RESISTANCE OF METAL SUBSTRATES BY PASSIVATING WITH AN ONIUM SALT-CONTAINING MATERIAL | PPG INDUSTRIES, INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-3935087-A | Method for electrodeposition of self-crosslinking cationic compositions | PPG INDUSTRIES, INC. (US) | 1976-01-27 | — | — | US | disclosed |