Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Deanol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA4 | P22748 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL7566788 | 0.86 | CA1 (0.42) | CA1CA4LMNAMEN1KMT2A | |
| Deanol SCHEMBL4621901 | 0.82 | FFAR3 (0.44) | LMNAMEN1KMT2AGRM4ALOX15 | |
| Deanol SCHEMBL28335877 | 0.79 | LMNA (0.40) | LMNAMEN1KMT2AGRM4ALOX15 | |
| Deanol SCHEMBL8040658 | 0.79 | MEN1 (0.39) | CA1LMNAMEN1KMT2AGRM4 | |
| Deanol SCHEMBL27486030 | 0.78 | MEN1 (0.50) | LMNAMEN1KMT2AGRM4 | |
| Deanol SCHEMBL609 | 0.78 | — | — | |
| Tromethamine SCHEMBL9115087 | 0.78 | MEN1 (0.56) | CA1CA4LMNAMEN1KMT2A | |
| Deanol SCHEMBL11871103 | 0.77 | MEN1 (0.37) | LMNAMEN1KMT2AGRM4ALOX15 | |
| Tromethamine SCHEMBL10775852 | 0.76 | MEN1 (0.53) | CA1CA4LMNAMEN1KMT2A | |
| Deanol SCHEMBL11861976 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0736890-B1 | Metal-containing compostition for forming electron-emitting device and methods of manufacturing electron-emitting device, electron source and image-forming apparatus | CANON KK (JP) | 2002-07-31 | — | — | EP | disclosed |
| EP-1124247-A1 | Metal-containing composition for forming electron-emitting device and methods of manufacturing electron-emitting device,electron source and image-forming apparatus | CANON KABUSHIKI KAISHA (JP) | 2001-08-16 | — | — | EP | disclosed |
| US-6270389-B1 | Method for forming an electron-emitting device using a metal-containing composition | CANON KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| US-6123876-A | COMPOUND CONTAINING AN ORGANIC ACID GROUP, A TRANSITION METAL AND AN ALCOHOL AMINE, AND WATER. | CANON KABUSHIKI KAISHA (JP) | 2000-09-26 | — | — | US | disclosed |
| EP-0736890-A1 | Metal-containing compostition for forming electron-emitting device and methods of manufacturing electron-emitting device, electron source and image-forming apparatus | CANON KABUSHIKI KAISHA (JP) | 1996-10-09 | — | — | EP | disclosed |