Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 7/20 | 0.40 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719786 | 0.85 | RAB9A (0.54) | GAARAB9AMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8500574 | 0.84 | RAB9A (0.52) | GAARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6721291 | 0.78 | SIGMAR1 (0.52) | GAARAB9AMAPTMEN1KMT2A | |
| SCHEMBL8181403 | 0.78 | SIGMAR1 (0.55) | GAARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6724169 | 0.77 | GAA (0.48) | GAARAB9AMAPTMEN1KMT2A | |
| SCHEMBL6720929 | 0.77 | SMN1; SMN2 (0.46) | GAARAB9AMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8501635 | 0.77 | SIGMAR1 (0.56) | GAARAB9AMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL8498689 | 0.76 | SMN1; SMN2 (0.46) | GAARAB9AMAPTMEN1KMT2A | |
| Cns-5161 SCHEMBL29370312 | 0.71 | GRIN2D (0.54) | GAARAB9AMAPTMEN1KMT2A | |
| Cns-5161 SCHEMBL499356 | 0.71 | GRIN2D (0.54) | GAARAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1896400-B1 | 18F OR 11C-LABELLED ALKYLTHIOPHENYL GUANIDINES FOR USE IN MEDICAL IMAGING | HAMMERSMITH IMANET LTD (GB) | 2013-10-16 | — | — | EP | disclosed |
| EP-1896400-A1 | IMAGING 18F OR 11C-LABELLED ALKYLTHIOPHENYL GUANIDINES | Hammersmith Imanet, Ltd (GB) | 2008-03-12 | — | — | EP | disclosed |
| WO-2006136846-A1 | IMAGING 18F OR 11C-LABELLED ALKYLTHIOPHENYL GUANIDINES | HAMMERSMITH IMANET LIMITED (GB) | 2006-12-28 | — | — | WO | disclosed |