SCHEMBL4622247

SCHEMBL4622247

CCCC[Zr](CCCC)(c1c(C)ccc2c1Cc1cc(C)ccc1-2)c1c(-c2cccc3ccccc23)ccc2c1Cc1cc(-c3cccc4ccccc34)ccc1-2

nearest known ligand 0.32

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.32
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31
CNR2 P34972 2/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
POLB P06746 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
RAB9A P51151 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL796972 0.88 CRHR1 (0.33) HTR7CA12CA1CA2CA9
SCHEMBL7601267 0.72 CA12 (0.34) HTR7CA12CA1CA2CA9
SCHEMBL797655 0.70 CRHR1 (0.33) HTR7CA12CA1CA2CA9
SCHEMBL797391 0.68
SCHEMBL29785059 0.68 MCL1 (0.47) CA12CA1CA2CA9KDM4E
SCHEMBL3137217 0.68 MCL1 (0.47) CA12CA1CA2CA9KDM4E
SCHEMBL4622250 0.67 EDNRB (0.36) CA12CA1CA2CA9CNR2
Hydrochloric Acid SCHEMBL8915892 0.67 MCL1 (0.36) HTR7CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL27463386 0.67 MCL1 (0.38) HTR7CA12CA1CA2CA9
Hydrochloric Acid SCHEMBL27551952 0.67 MCL1 (0.38) HTR7CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1219657-B1 POLYARYLENE AND METHOD FOR PRODUCTION THEREOF JAPAN SCIENCE & TECH AGENCY (JP) 2008-03-19 EP disclosed
US-6586554-B1 Polyarylene and method for production thereof JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) 2003-07-01 US disclosed
EP-1219657-A1 POLYARYLENE AND METHOD FOR PRODUCTION THEREOF Japan Science and Technology Corporation (JP) 2002-07-03 EP disclosed