SCHEMBL4622339

SCHEMBL4622339

[CH2]C(CC=CC(=O)O)(CC=CC(=O)O)CC=CC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
GABRR1 P24046 2/20 0.46
GABRR2 P28476 2/20 0.46
BLM P54132 2/20 0.46
LMNA P02545 2/20 0.46
GABRR3 A8MPY1 1/20 0.46
APEX1 P27695 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
TP53 P04637 1/20 0.40
EGLN1 Q9GZT9 1/20 0.40
EGLN3 Q9H6Z9 1/20 0.40
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5162276 0.78 TSHR (0.41) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL28637241 0.75 TSHR (0.42) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL14801551 0.74 TSHR (0.46) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL2467206 0.74 TSHR (0.46) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL455399 0.74 TSHR (0.46) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL3084517 0.74 TSHR (0.46) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL3023206 0.74 TSHR (0.46) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL2467205 0.74 TSHR (0.46) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL21521060 0.74 TSHR (0.46) TSHRGABRR1GABRR2BLMLMNA
SCHEMBL3023205 0.74 TSHR (0.46) TSHRGABRR1GABRR2BLMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3408301-B1 A PROCESS FOR OBTAINING A CATIONIC POLYMER WITH AN AT LEAST BIMODAL MOLECULAR WEIGHT DISTRIBUTION BASF SE (DE) 2020-03-11 EP claimed
EP-3408302-B1 CATIONIC POLYMER WITH AN AT LEAST BIMODAL MOLECULAR WEIGHT DISTRIBUTION BASF SE (DE) 2019-11-13 EP claimed
EP-3172305-B1 FABRIC AND HOME CARE TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2019-04-03 EP claimed
EP-3172302-B1 FABRIC AND HOME CARE TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2019-01-16 EP claimed
EP-3172301-B1 FABRIC AND HOME CARE TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2019-01-02 EP claimed
EP-3172303-B1 FABRIC AND HOME CARE TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2019-01-02 EP claimed
EP-3172298-B1 FABRIC AND HOME CARE TREATMENT COMPOSITIONS PROCTER & GAMBLE (US) 2019-01-02 EP claimed
EP-0393954-B1 A radiation-curable organopolysiloxane compound, method for the preparation thereof and method of forming a cured coating film SHINETSU CHEMICAL CO (JP) 1994-04-06 EP claimed
EP-1904442-A1 HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2008-04-02 EP disclosed
WO-2007005503-A1 HISTAMINE H3 RECEPTOR AGENTS, PREPARATION AND THERAPEUTIC USES ELI LILLY AND COMPANY (US) 2007-01-11 WO disclosed
EP-0819984-B1 Irradiation-sensitive recording material for flexographic printing plates DU PONT DEUTSCHLAND (DE) 2002-05-08 EP disclosed
EP-0819984-A1 Irradiation-sensitive composition and an irradiation-sensitive recording material containing the composition for flexographic printing plates DU PONT DE NEMOURS (DEUTSCHLAND) GMBH (DE) 1998-01-21 EP disclosed