Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.46 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.46 |
| ▸ | BLM | P54132 | 2/20 | 0.46 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.40 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3084515 | 1.00 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL1538365 | 0.90 | TSHR (0.42) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL712787 | 0.90 | TSHR (0.42) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL7076723 | 0.85 | GABRR1 (0.35) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL14801551 | 0.84 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL455399 | 0.84 | TSHR (0.46) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL4600709 | 0.83 | THRB (0.40) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL20625018 | 0.80 | TSHR (0.42) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL8076447 | 0.78 | TSHR (0.41) | TSHRGABRR1GABRR2BLMGABRR3 | |
| SCHEMBL2583139 | 0.78 | GABRR1 (0.33) | TSHRGABRR1GABRR2BLMGABRR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030194378-A1 | Novel aerosol formulation containing a polar fluorinated molecule | ASTRAZENECA AB (SE) | 2003-10-16 | — | — | US | claimed |
| EP-2222740-B1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2017-10-11 | — | — | EP | disclosed |
| US-9499649-B2 | Functionalized photoreactive compounds | ROLIC AG (CH) | 2016-11-22 | — | — | US | disclosed |
| US-8574454-B2 | Patternable liquid crystal polymer comprising thio-ether units | ROLIC AG (CH) | 2013-11-05 | — | — | US | disclosed |
| EP-2094815-B1 | PATTERNABLE LIQUID CRYSTAL POLYMER COMPRISING THIO-ETHER UNITS | ROLIC AG (CH) | 2012-06-27 | — | — | EP | disclosed |
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2010-10-21 | — | — | US | disclosed |
| EP-2222740-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | Rolic AG (CH) | 2010-09-01 | — | — | EP | disclosed |
| US-20100059709-A1 | PATTERNABLE LIQUID CRYSTAL POLYMER COMPRISING THIO-ETHER UNITS | ROLIC AG (CH) | 2010-03-11 | — | — | US | disclosed |
| EP-2094815-A1 | PATTERNABLE LIQUID CRYSTAL POLYMER COMPRISING THIO-ETHER UNITS | Rolic AG (CH) | 2009-09-02 | — | — | EP | disclosed |
| WO-2009080147-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ROLIC AG (CH) | 2009-07-02 | — | — | WO | disclosed |
| WO-2008077261-A1 | PATTERNABLE LIQUID CRYSTAL POLYMER COMPRISING THIO-ETHER UNITS | ROLIC AG (CH) | 2008-07-03 | — | — | WO | disclosed |
| US-20070272309-A1 | Composite Polymer Microfludic Control Device | EKSIGENT TECHNOLOGIES, LLC | 2007-11-29 | — | — | US | disclosed |
| EP-1303258-B1 | NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE | ASTRAZENECA AB (SE) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100266821-A1 | FUNCTIONALIZED PHOTOREACTIVE COMPOUNDS | ETV6, TERB1, VCL | TSHR 2049/4885GABRR1 2957/4885GABRR2 2628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.