Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 7/20 | 0.43 |
| ▸ | CES1 | P23141 | 7/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | EPRS1 | P07814 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6364782 | 0.83 | CES2 (0.48) | ALDH1A1ALOX15CES2CES1BCHE | |
| SCHEMBL9712390 | 0.82 | HPGD (0.42) | ALDH1A1ALOX15CES2CES1ADRA2A | |
| SCHEMBL106326 | 0.82 | ALDH1A1 (0.45) | ALDH1A1ALOX15CES2CES1ADRA2A | |
| SCHEMBL1192063 | 0.81 | CES2 (0.45) | ALDH1A1ALOX15CES2CES1ADRA2A | |
| SCHEMBL4621035 | 0.81 | CES2 (0.45) | CES2CES1ESR1ESR2BCHE | |
| SCHEMBL525011 | 0.80 | CES2 (0.67) | ALDH1A1ALOX15CES2CES1BCHE | |
| SCHEMBL3453035 | 0.80 | ALDH1A1 (0.44) | ALDH1A1ALOX15CES2CES1ESR1 | |
| SCHEMBL109636 | 0.78 | ALDH1A1 (0.45) | ALDH1A1ALOX15CES2CES1ADRA2A | |
| Benzoyl Chloride SCHEMBL8166169 | 0.78 | ALDH1A1 (0.36) | ALDH1A1ALOX15NPC1HTTRAB9A | |
| SCHEMBL1020497 | 0.77 | ALDH1A1 (0.43) | ALDH1A1ALOX15CES2CES1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1514864-B1 | Difluoralkyl aromatic compounds | SALTIGO GMBH (DE) | 2008-03-19 | — | — | EP | claimed |
| US-20050054733-A1 | Difluoroalkylaromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2005-03-10 | — | — | US | claimed |
| CN-117720495-A | Preparation method of novel amide-containing coumarin derivative, antibacterial effect of composition and application of composition in aspect of promoting plant growth | 贵州工业职业技术学院 | 2024-03-19 | — | — | CN | disclosed |
| CN-105175284-B | Amides compound, preparation method and its medical usage | 中国药科大学 | 2017-06-16 | — | — | CN | disclosed |
| CN-105175284-A | Amide compounds, preparation method and medical use thereof | UNIV CHINA PHARMA | 2015-12-23 | — | — | CN | disclosed |
| EP-1514864-A2 | Difluoralkyl aromatic compounds | Bayer Chemicals AG (DE) | 2005-03-16 | — | — | EP | disclosed |
| US-20050054733-A1 | Difluoroalkylaromatics | LANXESS DEUTSCHLAND GMBH (DE) | 2005-03-10 | — | — | US | disclosed |
| US-5648567-A | INTERMEDIATES FOR BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-07-15 | — | — | US | disclosed |
| US-5493048-A | REACTING METALLIZED FLUORO-TRIFLUOROMETHYLBENZENE DERIVATIVE WITH CARBON DIOXIDE AND PRODUCT IS THEN HYDROLYSED WITH AN ACID TO FORM ACID, SIMILARLY HALOGENATION GIVE ACID HALIDE AND WITH ALCOHOL GIVES ESTER | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-20 | — | — | US | disclosed |
| US-5117057-A | Insecticidal N' substituted-N-N'-disubstituted-hydrazines | ROHM AND HAAS COMPANY (US) | 1992-05-26 | — | — | US | disclosed |
| US-4870182-A | 4-Hydroxy-quinoline-3-carboxylic | BAYER AKTIENGESELLSCHAFT (DE) | 1989-09-26 | — | — | US | disclosed |
| US-4804760-A | Process for the preparation of 4-hydroxy-quinoline-3-carboxylic acids | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054733-A1 | Difluoroalkylaromatics | NQO1, TYR, FLI1 | ALDH1A1 393/4885ALOX15 2466/4885CES2 141/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.