Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 8/20 | 0.51 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.51 |
| ▸ | ITGAM | P11215 | 1/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683064 | 0.68 | SLC1A3 (1.00) | SLC1A3ITGB2ITGAMKDM4EPOLB | |
| SCHEMBL2559322 | 0.66 | POLB (0.60) | SLC1A3ITGB2ITGAMSTAT3KDM4E | |
| SCHEMBL46230 | 0.66 | MAPT (0.50) | ITGB2ITGAMKDM4EPOLBALDH1A1 | |
| SCHEMBL14363094 | 0.64 | L3MBTL1 (0.50) | SLC1A3ITGB2ITGAMSTAT3KDM4E | |
| SCHEMBL29494140 | 0.61 | SLC1A3 (0.79) | SLC1A3ITGB2ITGAMSTAT3KDM4E | |
| SCHEMBL1430422 | 0.61 | STAT3 (1.00) | SLC1A3ITGB2ITGAMSTAT3KDM4E | |
| SCHEMBL5145237 | 0.59 | SLC1A3 (1.00) | SLC1A3ITGB2ITGAMKDM4EPOLB | |
| SCHEMBL5145242 | 0.59 | SLC1A3 (1.00) | SLC1A3ITGB2ITGAMKDM4EPOLB | |
| SCHEMBL14472234 | 0.59 | TP53 (0.58) | KDM4EPOLBALDH1A1MAPTTDP1 | |
| SCHEMBL14472233 | 0.59 | TP53 (0.58) | KDM4EPOLBALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012005800-A1 | COMPOUNDS AND METHODS FOR REGULATING INTEGRIN CD11B/CD18 | ADHAERE PHARAMACEUTICALS, INC. (US) | 2012-01-12 | — | — | WO | disclosed |