⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15955896 | 0.80 | — | — | |
| SCHEMBL27905398 | 0.78 | — | — | |
| SCHEMBL779294 | 0.76 | — | — | |
| SCHEMBL6098734 | 0.76 | — | — | |
| SCHEMBL11277241 | 0.76 | — | — | |
| SCHEMBL19899968 | 0.76 | TSHR (0.41) | — | |
| SCHEMBL10447882 | 0.76 | — | — | |
| SCHEMBL9183806 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL1867473 | 0.72 | ALDH1A1 (0.42) | — | |
| SCHEMBL8727419 | 0.72 | TDP1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119504530-A | Aromatic ether compound, preparation method and application thereof, and method for recovering noble metal by solvent extraction | 湖南理工学院 | 2025-02-25 | — | — | CN | disclosed |
| CN-115746152-B | Thallium ion adsorbent and preparation method thereof | 宁波大学 | 2024-02-06 | — | — | CN | disclosed |
| CN-115746152-A | Thallium ion adsorbent and preparation method thereof | 宁波大学 | 2023-03-07 | — | — | CN | disclosed |
| US-11084783-B2 | O-alkyl-benzylideneguanidine derivatives and therapeutic use for the treatment of disorders associated with an accumulation of misfolded proteins | INFLECTIS BIOSCIENCE (FR) | 2021-08-10 | — | — | US | disclosed |
| US-20210106944-A1 | ABSORBENT COMPOSITIONS INCLUDING AMINO-SILOXANES | BAKER HUGHES ENERGY SERVICES LLC | 2021-04-15 | — | — | US | disclosed |
| CN-106488907-B | O-alkyl-benzylidene guanidine derivatives and their therapeutic use for the treatment of diseases associated with accumulation of misfolded proteins | 英费列特斯生命科学公司 | 2021-01-29 | — | — | CN | disclosed |
| US-10675257-B2 | Method of treating cancer with a combination of benzylideneguanidine derivatives and chemotherapeutic agent | INFLECTIS BIOSCIENCE (FR) | 2020-06-09 | — | — | US | disclosed |
| US-20200102269-A1 | O-ALKYL-BENZYLIDENEGUANIDINE DERIVATIVES AND THERAPEUTIC USE FOR THE TREATMENT OF DISORDERS ASSOCIATED WITH AN ACCUMULATION OF MISFOLDED PROTEINS | INFLECTIS BIOSCIENCE (FR) | 2020-04-02 | — | — | US | disclosed |
| EP-3609604-A1 | ABSORBENT COMPOSITIONS INCLUDING AMINO-SILOXANES | GE Oil & Gas, Inc. (US) | 2020-02-19 | — | — | EP | disclosed |
| US-10544093-B2 | O-alkyl-benzylideneguanidine derivatives and therapeutic use for the treatment of disorders associated an accumulation of misfolded proteins | INFLECTIS BIOSCIENCE (FR) | 2020-01-28 | — | — | US | disclosed |
| US-4659726-A | ANTICOAGULANTS | KANEBO, LTD. (JP) | 1987-04-21 | — | — | US | disclosed |
| EP-0159677-A2 | Novel 4,5-bis(4-methoxyphenyl)-2-(pyrrol-2-yl)thiazoles, process for the preparation thereof and pharmaceutical composition containing the same | KANEBO, LTD. (JP) | 1985-10-30 | — | — | EP | disclosed |
| US-4528195-A | Imidazole derivatives and salts thereof, their synthesis and intermediates and pharmaceutical formulations | THOROGOOD PETER B (GB) | 1985-07-09 | — | — | US | disclosed |
| EP-0003560-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF, THEIR SYNTHESIS, AND PHARMACEUTICAL FORMULATIONS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-02 | — | — | EP | disclosed |
| US-4416895-A | ANTICOAGULANTS, ANTISHOCK AGENTS | BURROUGHS WELLCOME CO. (US) | 1983-11-22 | — | — | US | disclosed |
| US-4385927-A | ETHER OF N-2,3-DICHLOROPHENYL P-HYDROXYBENZAMIDE | HODOGAYA CHEMICAL CO., LTD. (JP) | 1983-05-31 | — | — | US | disclosed |
| EP-0003560-A2 | Imidazole derivatives and salts thereof, their synthesis, and pharmaceutical formulations | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-08-22 | — | — | EP | disclosed |
| US-4011327-A | FUNGICIDES | RESEARCH CORPORATION (US) | 1977-03-08 | — | — | US | disclosed |
| US-3993768-A | FUNGICIDES | SYNTEX (U.S.A.) INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-RE28935-E | PSYCHOSEDATIVES, ANTICONVULSANTS | BOEHRINGER INGELHEIM GMBH (DT) | 1976-08-17 | — | — | US | disclosed |