SCHEMBL4623541

SCHEMBL4623541

COC1CCC(NOC(=O)O)CC1

nearest known ligand 0.41

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 1/20 0.41
CD38 P28907 5/20 0.32
MAPK8 P45983 5/20 0.32
MAPK9 P45984 1/20 0.32
BRD4 O60885 2/20 0.32
ADORA3 P0DMS8 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2B6 P20813 1/20 0.31
CYP2C19 P33261 1/20 0.31
CCNA2 P20248 2/20 0.30
CDK2 P24941 2/20 0.30
GSK3A P49840 1/20 0.30
GSK3B P49841 1/20 0.30
MAPK10 P53779 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4625426 1.00 EPHX2 (0.41) EPHX2CD38MAPK8MAPK9BRD4
Hydrochloric Acid SCHEMBL4624697 0.82 EPHX2 (0.41) EPHX2CD38MAPK8MAPK9BRD4
Hydrochloric Acid SCHEMBL4625608 0.82 EPHX2 (0.41) EPHX2CD38MAPK8MAPK9BRD4
SCHEMBL3539009 0.75 EPHX2 (0.51) EPHX2CD38BRD4CYP2D6CYP2B6
SCHEMBL3229882 0.75 EPHX2 (0.51) EPHX2CD38BRD4CYP2D6CYP2B6
SCHEMBL3229891 0.75 EPHX2 (0.51) EPHX2CD38BRD4CYP2D6CYP2B6
Bicarbonate SCHEMBL9845632 0.75
Hydrochloric Acid SCHEMBL3546089 0.73 EPHX2 (0.50) EPHX2CD38BRD4CYP2D6CYP2B6
Hydrochloric Acid SCHEMBL28190843 0.73 EPHX2 (0.50) EPHX2CD38BRD4CYP2D6CYP2B6
Hydrochloric Acid SCHEMBL2070160 0.73 EPHX2 (0.50) EPHX2CD38BRD4CYP2D6CYP2B6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1309562-B1 4-ALKOXY CYCLOHEXANE-1 AMINO CARBOXYLIC ACID ESTERS AND METHOD FOR THE PRODUCTION THEREOF BAYER CROPSCIENCE AG (DE) 2008-05-07 EP disclosed