Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CD38 | P28907 | 6/20 | 0.39 |
| ▸ | BRD4 | O60885 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | GSK3A | P49840 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3229882 | 1.00 | EPHX2 (0.51) | EPHX2CD38BRD4POLBCYP2D6 | |
| SCHEMBL3229891 | 1.00 | EPHX2 (0.51) | EPHX2CD38BRD4POLBCYP2D6 | |
| SCHEMBL20488506 | 0.88 | EPHX2 (0.45) | EPHX2CD38BRD4POLBNPSR1 | |
| SCHEMBL20488504 | 0.88 | EPHX2 (0.45) | EPHX2CD38BRD4POLBNPSR1 | |
| SCHEMBL12409147 | 0.83 | EPHX2 (0.51) | EPHX2CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL12409405 | 0.83 | EPHX2 (0.51) | EPHX2CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL10082245 | 0.83 | EPHX2 (0.51) | EPHX2CD38CYP2D6CYP2B6CYP2C19 | |
| SCHEMBL4715595 | 0.82 | PDE7A (0.43) | EPHX2POLB | |
| Hydrochloric Acid SCHEMBL3546089 | 0.81 | EPHX2 (0.50) | EPHX2CD38BRD4CYP2D6CYP2B6 | |
| Hydrochloric Acid SCHEMBL2070160 | 0.81 | EPHX2 (0.50) | EPHX2CD38BRD4CYP2D6CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7803967-B2 | 4-alkoxy-cyclohexane-1-amino-carboxylic esters and processes for their preparation | BAYER CROPSCIENCE AG (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20090156402-A1 | 4-ALKOXY-CYCLOHEXANE-1-AMINO-CARBOXYLIC ESTERS AND PROCESSES FOR THEIR PREPARATION | BAYER CROPSCIENCE AG (DE) | 2009-06-18 | — | — | US | disclosed |
| US-7511153-B2 | 4-alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2009-03-31 | — | — | US | disclosed |
| US-20070043219-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2007-02-22 | — | — | US | disclosed |
| US-7148377-B2 | 4-Alkoxy cyclohexane-1-amino-carboxylic acid esters and method for the production thereof | BAYER CROPSCIENCE AG (DE) | 2006-12-12 | — | — | US | disclosed |
| US-20040039223-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2004-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070043219-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | ALDH7A1, DDC, ABAT | EPHX2 268/4885CD38 1909/4885BRD4 3956/4885 |
| US-20090156402-A1 | 4-ALKOXY-CYCLOHEXANE-1-AMINO-CARBOXYLIC ESTERS AND PROCESSES FOR THEIR PREPARATION | DDT, CYP4B1, ALDH7A1 | EPHX2 177/4885CD38 1780/4885BRD4 3560/4885 |
| US-20040039223-A1 | 4-Alkoxy cyclohexane-1 amino carboxylic acid esters and method for the production thereof | ALDH7A1, CYP51A1, ABAT | EPHX2 354/4885CD38 1915/4885BRD4 3778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.