SCHEMBL4623922

SCHEMBL4623922

CCOc1ccc(/C=C/C(=O)O)cc1OCC

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.84
KMT2A Q03164 2/20 0.84
GAA P10253 1/20 0.84
LMNA P02545 3/20 0.80
POLB P06746 2/20 0.80
MEN1 O00255 1/20 0.72
AKR1C3 P42330 1/20 0.67
ALDH1A1 P00352 4/20 0.64
SMN1; SMN2 Q16637 2/20 0.64
HPGD P15428 1/20 0.64
ALOX15 P16050 1/20 0.64
MAPK1 P28482 1/20 0.64
HSD17B10 Q99714 1/20 0.64
MAPT P10636 2/20 0.63
NPC1 O15118 1/20 0.63
RAB9A P51151 1/20 0.63
SNCA P37840 2/20 0.62
TOP2A P11388 3/20 0.60
CA12 O43570 1/20 0.56
CA1 P00915 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7247313 1.00 KDM4E (0.84) KDM4EKMT2AGAALMNAPOLB
SCHEMBL30739528 1.00 KDM4E (0.84) KDM4EKMT2AGAALMNAPOLB
SCHEMBL7246269 0.93 KDM4E (0.82) KDM4EKMT2AGAALMNAPOLB
SCHEMBL4623935 0.93 KDM4E (0.82) KDM4EKMT2AGAALMNAPOLB
SCHEMBL3690896 0.92 KDM4E (0.80) KDM4EKMT2AGAALMNAPOLB
SCHEMBL30966315 0.92 KDM4E (0.80) KDM4EKMT2AGAALMNAPOLB
SCHEMBL3688297 0.92 KDM4E (0.77) KDM4EKMT2AGAALMNAPOLB
SCHEMBL3688296 0.92 KDM4E (0.77) KDM4EKMT2AGAALMNAPOLB
SCHEMBL3690899 0.92 KDM4E (0.80) KDM4EKMT2AGAALMNAPOLB
SCHEMBL11682531 0.92 KDM4E (1.00) KDM4EKMT2AGAALMNAPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117801749-A Adhesive composition for LCD and preparation method thereof 西安思摩威新材料有限公司 2024-04-02 CN claimed
CN-117380269-B Oil-soluble organic molybdenum catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-04-05 CN disclosed
CN-117801749-A Adhesive composition for LCD and preparation method thereof 西安思摩威新材料有限公司 2024-04-02 CN disclosed
CN-117380269-A Oil-soluble organic molybdenum catalyst and preparation method and application thereof 北京高新利华科技股份有限公司 2024-01-12 CN disclosed
US-10227620-B2 Method for biotechnological production of methylized cinnamic acids and cinnamic acid esters, methylized phenethylamines and the coupling products thereof, particularly of cinnamic acid amides SYMRISE AG (DE) 2019-03-12 US disclosed
US-20160281118-A1 METHOD FOR BIOTECHNOLOGICAL PRODUCTION OF METHYLIZED CINNAMIC ACIDS AND CINNAMIC ACID ESTERS, METHYLIZED PHENETHYLAMINES AND THE COUPLING PRODUCTS THEREOF, PARTICULARLY OF CINNAMIC ACID AMIDES SYMRISE AG (DE) 2016-09-29 US disclosed
EP-0860455-B1 Photocrosslinkable polymers ROLIC AG (CH) 2008-06-04 EP disclosed
US-6632909-B2 Alkylenedi- acrylates and acrylamides containing phenyl groups substituted with at least two alkoxy or fluoroalkoxy groups; use in orientation layers for liquid crystals, and in optical components, in particular hybrid layer elements. ROLIC AG (CH) 2003-10-14 US disclosed
US-20020128231-A1 Aryl-indane compounds EASTMAN CHEMICAL COMPANY 2002-09-12 US disclosed
US-20020061996-A1 Photocrosslinkable polymers BUCHECKER RICHARD (CH) 2002-05-23 US disclosed
WO-2002030915-A2 ARYL-INDANE COMPOUNDS FOR USE AS INHIBITORS OF P-GLYCOPROTEIN MEDIATED TRANSPORT AVLAN LIMITED (GB) 2002-04-18 WO disclosed
EP-0860455-A2 Photocrosslinkable polymers Rolic AG (CH) 1998-08-26 EP disclosed
US-RE32944-E Aromatic carboxylic amide derivatives Kissei Yakuhin Kogyo Kabushiki (JP) 1989-06-06 US disclosed
US-4070484-A Antiallergic composition containing aromatic carboxylic amide derivatives and method of using the same KISSEI PHARMACEUTICAL CO., LTD. (JA) 1978-01-24 US disclosed
US-3940422-A ANTIALLERGEN KISSEI YAKUHIN KOGYO KABUSHIKI KAISHA (JA) 1976-02-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128231-A1 Aryl-indane compounds ABCB1, ABCC1, ABCG2 KDM4E 3633/4885KMT2A 4047/4885GAA 415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.