Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.82 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.82 |
| ▸ | GAA | P10253 | 1/20 | 0.82 |
| ▸ | POLB | P06746 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.64 |
| ▸ | ACHE | P22303 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | FDPS | P14324 | 3/20 | 0.55 |
| ▸ | SNCA | P37840 | 1/20 | 0.55 |
| ▸ | TOP2A | P11388 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7246269 | 1.00 | KDM4E (0.82) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL7525311 | 0.96 | KDM4E (0.86) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL7525306 | 0.96 | KDM4E (0.86) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL7247313 | 0.93 | KDM4E (0.84) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL4623922 | 0.93 | KDM4E (0.84) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL30739528 | 0.93 | KDM4E (0.84) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL11682531 | 0.90 | KDM4E (1.00) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL11682535 | 0.90 | KDM4E (1.00) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL11231174 | 0.89 | KDM4E (0.90) | KDM4EKMT2AGAAPOLBMEN1 | |
| SCHEMBL3694597 | 0.89 | KDM4E (1.00) | KDM4EKMT2AGAAPOLBAKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0860455-B1 | Photocrosslinkable polymers | ROLIC AG (CH) | 2008-06-04 | — | — | EP | disclosed |
| US-6632909-B2 | Alkylenedi- acrylates and acrylamides containing phenyl groups substituted with at least two alkoxy or fluoroalkoxy groups; use in orientation layers for liquid crystals, and in optical components, in particular hybrid layer elements. | ROLIC AG (CH) | 2003-10-14 | — | — | US | disclosed |
| US-20020061996-A1 | Photocrosslinkable polymers | BUCHECKER RICHARD (CH) | 2002-05-23 | — | — | US | disclosed |
| EP-0860455-A2 | Photocrosslinkable polymers | Rolic AG (CH) | 1998-08-26 | — | — | EP | disclosed |