SCHEMBL4623964

SCHEMBL4623964

CCN1C(=O)C(=CC=C2Sc3ccccc3N2CC)N(CC)C1=S

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 14/20 0.74
KMT2A Q03164 14/20 0.74
MAPT P10636 12/20 0.74
ALDH1A1 P00352 10/20 0.74
MAPK1 P28482 5/20 0.74
NPC1 O15118 4/20 0.74
RAB9A P51151 4/20 0.74
THRB P10828 2/20 0.74
SMN1; SMN2 Q16637 5/20 0.67
LMNA P02545 1/20 0.61
OPRK1 P41145 1/20 0.56
USP2 O75604 3/20 0.54
CRHBP P24387 2/20 0.54
CRHR2 Q13324 2/20 0.54
IDE P14735 1/20 0.54
HPGD P15428 2/20 0.51
HTT P42858 2/20 0.51
TDP1 Q9NUW8 2/20 0.49
RECQL P46063 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10036030 1.00 MEN1 (0.74) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL13026070 0.90 KMT2A (0.87) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL10036033 0.90 MEN1 (0.87) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL13709032 0.89 MEN1 (0.69) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL12388178 0.87 MEN1 (0.84) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL30767820 0.80 MEN1 (0.87) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL7022919 0.80 MEN1 (0.87) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL10036064 0.80 MEN1 (0.87) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL7022922 0.80 MEN1 (0.87) MEN1KMT2AMAPTALDH1A1MAPK1
SCHEMBL9191749 0.80 MEN1 (0.75) MEN1KMT2AMAPTALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0443861-B2 Organic electroluminescence device SUMITOMO CHEMICAL CO (JP) 2008-05-28 EP claimed
EP-0443861-B1 Organic electroluminescence device SUMITOMO CHEMICAL CO (JP) 1995-07-05 EP claimed
US-5317169-A Using a polyarylenevinylene as a light emitting layer; uniformity of emission over a large surface; efficiency SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-05-31 US claimed
EP-0443861-A2 Organic electroluminescence device SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-08-28 EP claimed
EP-0738928-B1 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORP (JP) 2001-06-20 EP disclosed
US-5744511-A BLEND OF COUMARIN DYES, ACID GENERATOR AND ARYL BORATE TOKUYAMA CORPORATION (JP) 1998-04-28 US disclosed
EP-0738928-A2 Visible-ray polymerization initiator and visible-ray polymerizable composition TOKUYAMA CORPORATION (JP) 1996-10-23 EP disclosed