SCHEMBL4623975

SCHEMBL4623975

CC(CC(=O)O)C1CCCCC1.CCC(C(=O)O)C(C)C1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.42
EPHX1 P07099 3/20 0.36
SHBG P04278 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
EPHX2 P34913 2/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32
HIF1A Q16665 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
HRH2 P25021 2/20 0.31
HRH1 P35367 2/20 0.31
HRH4 Q9H3N8 2/20 0.31
HRH3 Q9Y5N1 2/20 0.31
REN P00797 1/20 0.31
ACE P12821 1/20 0.31
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
MMP2 P08253 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2180612 0.88 SHBG (0.45) ALDH1A1EPHX1SHBGSMN1; SMN2EPHX2
SCHEMBL1208925 0.85 ALDH1A1 (0.55) ALDH1A1EPHX1SHBGSMN1; SMN2CYP2C19
SCHEMBL8651989 0.85 ALDH1A1 (0.55) ALDH1A1EPHX1SHBGSMN1; SMN2CYP2C19
SCHEMBL6808670 0.85 ALDH1A1 (0.55) ALDH1A1EPHX1SHBGSMN1; SMN2CYP2C19
SCHEMBL4093508 0.79 SHBG (0.48) ALDH1A1EPHX1SHBGSMN1; SMN2TDP1
SCHEMBL5967438 0.75
SCHEMBL28014448 0.74 ALDH1A1 (0.39) ALDH1A1EPHX1SHBGSMN1; SMN2CYP2C9
SCHEMBL11453751 0.73 SHBG (0.43) ALDH1A1EPHX1SHBGSMN1; SMN2EPHX2
SCHEMBL5682022 0.73 SMN1; SMN2 (0.44) ALDH1A1EPHX1SHBGSMN1; SMN2CYP2C9
SCHEMBL10646074 0.73 SHBG (0.59) ALDH1A1EPHX1SHBGSMN1; SMN2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1447102-B1 Cyclohexylethan-1-yl ester mixtures as malodour counteractants and methods for using same INT FLAVORS & FRAGRANCES INC (US) 2008-06-04 EP claimed