SCHEMBL4623976

SCHEMBL4623976

CC(CCC(C(=O)O)C(C(=O)O)C(C)C1CCCCC1)C1CCCCC1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.33
ALDH1A1 P00352 2/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
HIF1A Q16665 1/20 0.33
EPHX1 P07099 3/20 0.32
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
MMP2 P08253 2/20 0.32
CA9 Q16790 2/20 0.32
MEN1 O00255 1/20 0.32
MITF O75030 1/20 0.32
KMT2A Q03164 1/20 0.32
CPB2 Q96IY4 1/20 0.31
GAA P10253 1/20 0.30
RAB9A P51151 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27488386 0.79 GABRR1 (0.43) SMN1; SMN2ALDH1A1CYP2C9CYP2C19HIF1A
SCHEMBL27488749 0.77 GABRR1 (0.45) SMN1; SMN2ALDH1A1CYP2C9CYP2C19HIF1A
SCHEMBL28014448 0.75 ALDH1A1 (0.39) SMN1; SMN2ALDH1A1CYP2C9CYP2C19HIF1A
SCHEMBL7636264 0.75 ALDH1A1 (0.36) SMN1; SMN2ALDH1A1CYP2C9CYP2C19HIF1A
SCHEMBL27489072 0.73 GABRR1 (0.45) SMN1; SMN2ALDH1A1
SCHEMBL4991459 0.72 ALDH1A1 (0.45) SMN1; SMN2ALDH1A1CYP2C9CYP2C19HIF1A
SCHEMBL1226217 0.72 ALDH1A1 (0.44) SMN1; SMN2ALDH1A1EPHX1MEN1KMT2A
SCHEMBL2180612 0.72 SHBG (0.45) SMN1; SMN2ALDH1A1CYP2C9CYP2C19HIF1A
SCHEMBL4986408 0.70 ALDH1A1 (0.50) SMN1; SMN2ALDH1A1CYP2C9CYP2C19HIF1A
SCHEMBL4990099 0.70 ALDH1A1 (0.42) SMN1; SMN2ALDH1A1EPHX1MEN1MITF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1447102-B1 Cyclohexylethan-1-yl ester mixtures as malodour counteractants and methods for using same INT FLAVORS & FRAGRANCES INC (US) 2008-06-04 EP claimed