SCHEMBL4624322

SCHEMBL4624322

CS(=O)(=O)ON=C(c1ccc(OCCCOc2ccc(C(=NOS(C)(=O)=O)C(F)(F)F)cc2)cc1)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA9 Q16790 2/20 0.44
L3MBTL1 Q9Y468 2/20 0.41
GAA P10253 2/20 0.41
FURIN P09958 1/20 0.39
PLA2G4B P0C869 1/20 0.39
TMPRSS2 O15393 1/20 0.38
POLB P06746 1/20 0.37
PRSS1 P07477 1/20 0.37
MAPT P10636 1/20 0.37
RAB9A P51151 1/20 0.37
TP53 P04637 1/20 0.37
TSHR P16473 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4624320 1.00 CA12 (0.44) CA12CA1CA2CA9L3MBTL1
SCHEMBL12848022 1.00 CA12 (0.44) CA12CA1CA2CA9L3MBTL1
SCHEMBL26049411 0.94 CA12 (0.40) CA12CA1CA2CA9L3MBTL1
SCHEMBL6756919 0.92 GAA (0.40) CA12CA1CA2CA9L3MBTL1
SCHEMBL6756922 0.92 GAA (0.40) CA12CA1CA2CA9L3MBTL1
SCHEMBL14454603 0.92 CA12 (0.39) CA12CA1CA2CA9L3MBTL1
SCHEMBL965125 0.92 PKM (0.47) CA12CA1CA2CA9L3MBTL1
SCHEMBL19880237 0.91 CA12 (0.39) CA12CA1CA2CA9L3MBTL1
SCHEMBL14454598 0.91 RAB9A (0.41) CA12CA1CA2CA9L3MBTL1
SCHEMBL14454596 0.91 CA12 (0.43) CA12CA1CA2CA9L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1344109-B1 ONIUM SALTS AND THE USE THEROF AS LATENT ACIDS CIBA HOLDING INC (CH) 2008-05-07 EP disclosed
US-6929896-B2 Onium salts and the use therof as latent acids CIBA SPECIALTY CHEMICALS CORPORATION (US) 2005-08-16 US disclosed
US-6713612-B2 Sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-03-30 US disclosed
US-20040053158-A1 Onium salts and the use therof as latent acids CIBA SPECIALTY CHEMICALS CORP. 2004-03-18 US disclosed
US-20030224298-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030224298-A1 Novel sulfonyldiazomethanes, photoacid generators, resist compositions, and patterning process VEGFA, DNMT3A, PIM3 CA12 3341/4885CA1 3621/4885CA2 2452/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.