Phosphoric Acid

Phosphoric Acid

SCHEMBL4624441

CC(O)COCC(C)O.O=P(O)(O)O

nearest known ligand 0.50

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Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRB1ADRB2ADRB3CYP11B1DPP4FGFR1FGFR2FGFR3FGFR4HRH1JAK1JAK2JAK3KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITNAOPRD1OPRK1OPRM1PPDGFRBPIK3CDSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASMOTYK2polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 1/20 0.50
MAPK1 P28482 1/20 0.40
TDP1 Q9NUW8 2/20 0.37
PGK1 P00558 1/20 0.34
PGK2 P07205 1/20 0.34
FYN P06241 1/20 0.33
MAOA P21397 1/20 0.33
SLC6A2 P23975 1/20 0.33
HTR2C P28335 1/20 0.33
HTR2B P41595 1/20 0.33
SLC6A3 Q01959 1/20 0.33
LMNA P02545 1/20 0.33
LPAR5 Q9H1C0 1/20 0.33
TSHR P16473 1/20 0.33
MAPT P10636 1/20 0.33
LAP3 P28838 3/20 0.32
MPI P34949 1/20 0.32
PGD P52209 1/20 0.32
ANPEP P15144 3/20 0.32
ERAP1 Q9NZ08 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5524685 0.85
SCHEMBL10073780 0.85
SCHEMBL35798 0.85
SCHEMBL5528595 0.85
SCHEMBL30368919 0.82 HSD17B10 (0.60) HSD17B10MAPK1TDP1FYNMAOA
SCHEMBL28174066 0.82 HSD17B10 (0.60) HSD17B10MAPK1TDP1FYNMAOA
SCHEMBL4624439 0.82 HSD17B10 (0.40) HSD17B10MAPK1TDP1PGK1PGK2
Phosphoric Acid SCHEMBL1074271 0.80 CA1 (0.47) HSD17B10MAPK1TDP1TSHR
Phosphoric Acid SCHEMBL9131068 0.80 HSD17B10 (0.39) HSD17B10MAPK1LMNATSHR
Methoxymethane SCHEMBL728290 0.79 HSD17B10 (0.57) HSD17B10MAPK1TDP1FYNMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100402004-C Gelling cold pack TEMPRA TECH INC (US) 2008-07-16 CN disclosed
EP-1100419-B1 GELLING COLD PACK TEMPRA TECH INC (US) 2008-05-28 EP disclosed
EP-1100419-A4 GELLING COLD PACK TEMPRA TECH INC (US) 2005-08-24 EP disclosed
CN-1321074-A gelled cooling pack TEMPRA TECH INC (US) 2001-11-07 CN disclosed
EP-1100419-A1 GELLING COLD PACK Tempra Technology, Inc. (US) 2001-05-23 EP disclosed
US-6099555-A Gelling cold pack TEMPRA TECHNOLOGY, INC. (US) 2000-08-08 US disclosed
WO-2000006063-A9 GELLING COLD PACK TEMPRA TECH INC (US) 2000-07-27 WO disclosed
US-6042732-A Starch/cationic polymer combinations as coagulants for the mining industry NALCO CHEMICAL COMPANY 2000-03-28 US disclosed
WO-2000006063-A1 GELLING COLD PACK TEMPRA TECHNOLOGY, INC. (US) 2000-02-10 WO disclosed