Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.35 |
| ▸ | TNF | P01375 | 1/20 | 0.34 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | TAF1 | P21675 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.32 |
| ▸ | AHR | P35869 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | PRKACA | P17612 | 1/20 | 0.31 |
| ▸ | PRKACG | P22612 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9333941 | 0.76 | PDPK1 (0.36) | PDPK1TNFRIPK1NR3C1PGR | |
| SCHEMBL1875458 | 0.74 | TNF (0.42) | PDPK1TNFRIPK1BRD4TAF1 | |
| SCHEMBL9336722 | 0.71 | DHPS (0.33) | AHR | |
| SCHEMBL8055277 | 0.71 | TNF (0.39) | PDPK1TNFRIPK1NR3C1PGR | |
| SCHEMBL16692645 | 0.68 | TNF (0.37) | PDPK1TNFRIPK1NR3C1PGR | |
| SCHEMBL17084654 | 0.68 | TNF (0.37) | PDPK1TNFRIPK1NR3C1PGR | |
| SCHEMBL25079005 | 0.67 | TNF (0.39) | PDPK1TNFRIPK1NR3C1PGR | |
| SCHEMBL29488158 | 0.67 | TNF (0.39) | PDPK1TNFRIPK1NR3C1PGR | |
| SCHEMBL21848959 | 0.67 | TNF (0.53) | PDPK1TNFRIPK1NR3C1PGR | |
| SCHEMBL8388759 | 0.67 | PTPN22 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0446131-B1 | Keratinous fibres dyeing process with substituted monohydroxy indols and compositions | OREAL (FR) | 1994-05-04 | — | — | EP | claimed |
| EP-1067950-B1 | NEO-TRYPTOPHAN | MAYO FOUNDATION (US) | 2008-05-14 | — | — | EP | disclosed |