Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPRE | P23469 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 3/20 | 0.35 |
| ▸ | PRKACG | P22612 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25079005 | 0.77 | TNF (0.39) | TNFRIPK1TYRAHRKEAP1 | |
| SCHEMBL29488158 | 0.77 | TNF (0.39) | TNFRIPK1TYRAHRKEAP1 | |
| SCHEMBL8055277 | 0.77 | TNF (0.39) | TNFRIPK1TYRAHRKEAP1 | |
| SCHEMBL1374474 | 0.76 | TNF (0.54) | TNFRIPK1TYRAHRKEAP1 | |
| SCHEMBL29591462 | 0.76 | TNF (0.54) | TNFRIPK1TYRAHRKEAP1 | |
| SCHEMBL9316145 | 0.74 | GAA (0.39) | TNFRIPK1TYRAHRKEAP1 | |
| SCHEMBL4624602 | 0.74 | PDPK1 (0.35) | TNFRIPK1TYRAHRKEAP1 | |
| SCHEMBL17087492 | 0.73 | ERN1 (0.47) | TNFRIPK1KEAP1PDPK1BACE1 | |
| SCHEMBL9315426 | 0.73 | MCL1 (0.42) | TNFRIPK1ALOX15BRD4BACE1 | |
| SCHEMBL1880644 | 0.73 | CA1 (0.42) | TNFRIPK1TYRAHRKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103517703-B | Stain and application thereof | 天野酶制品株式会社 | 2016-11-09 | — | — | CN | claimed |
| EP-2623093-B1 | DYE FOR KERATIN FIBERS USING BILIRUBIN OXIDASE AND INDOLE DERIVATIVES | AMANO ENZYME INC (JP) | 2016-05-25 | — | — | EP | claimed |
| CN-103998016-B | Employ the dyeing of the keratin fiber of indole analog | AMANO ENZYME INC. (JP) | 2015-09-16 | — | — | CN | claimed |
| US-20140359950-A1 | DYEING OF KERATIN FIBERS USING INDOLE ANALOGUE | AMANO ENZYME INC. (JP) | 2014-12-11 | — | — | US | claimed |
| WO-2011073941-A1 | USE OF A POLYMER AS AN ANTIOXIDANT AGENT | L'OREAL (FR) | 2011-06-23 | — | — | WO | claimed |
| US-7704285-B2 | Composition for coloring a keratin material, comprising at least two components, and coloring processes | L'OREAL S.A. (FR) | 2010-04-27 | — | — | US | claimed |
| US-20100005599-A1 | COMPOSITION FOR COLORING A KERATIN MATERIAL, COMPRISING AT LEAST TWO COMPONENTS, AND COLORING PROCESSES | PRUCHE FRANCIS | 2010-01-14 | — | — | US | claimed |
| WO-2009010684-A2 | PROCESS FOR DYEING HUMAN KERATIN MATERIALS USING AN ORTHO-DIPHENOL AND DEHYDROASCORBIC ACID OR A MONOMERIC, POLYMERIC OR ISOMERIC DERIVATIVE THEREOF | L'OREAL (FR) | 2009-01-22 | — | — | WO | claimed |
| EP-1405627-B1 | Antipenetrating hair pretreatment composition based on polyethelenoxide polymer(s) and process using said composition for limiting skin penetration by colourants | OREAL (FR) | 2008-04-30 | — | — | EP | claimed |
| US-7270685-B2 | Coloring composition for keratin fibres comprising a system limiting the transcutaneous passage of an oxidation dye | L'OREAL (FR) | 2007-09-18 | — | — | US | claimed |
| EP-1348421-A2 | A method of thickening and styling human keratinous fibres using a particular catalytic system | L'OREAL (FR) | 2003-10-01 | — | — | EP | claimed |
| US-20030163878-A1 | Dyeing composition, method for obtaining the same and use for colouring the skin and/or keratinous fibres | L'OREAL (FR) | 2003-09-04 | — | — | US | claimed |
| US-20030103917-A1 | Dyeing composition promoting natural pigmentation, method for obtaining same and use for colouring the skin and/or keratinous fibres | L'OREAL (FR) | 2003-06-05 | — | — | US | claimed |
| WO-2002076422-A1 | USE OF A MIXTURE COMPRISING MN(II) AND/OR ZN(II) WITH A HYDROGENOCARBONATE AND AT LEAST AN ORTHODIPHENOL, AS AGENT REDUCING ADHESION OF MICRO-ORGANISMS | L'OREAL (FR) | 2002-10-03 | — | — | WO | claimed |
| US-20020124330-A1 | Coloration composition, process for obtaining the same and its use for the coloration of keratin fibres | L'OREAL (FR) | 2002-09-12 | — | — | US | claimed |
| EP-1229892-A1 | DYEING COMPOSITION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES | L'OREAL (FR) | 2002-08-14 | — | — | EP | claimed |
| EP-1229890-A1 | DYEING COMPOSITION PROMOTING NATURAL PIGMENTATION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES | L'OREAL (FR) | 2002-08-14 | — | — | EP | claimed |
| EP-1210931-A1 | Keratinic fibres dyeing composition | L'OREAL (FR) | 2002-06-05 | — | — | EP | claimed |
| WO-2002030371-A1 | DYEING COMPOSITION PROMOTING NATURAL PIGMENTATION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES | L"OREAL (FR) | 2002-04-18 | — | — | WO | claimed |
| WO-2002030375-A1 | DYEING COMPOSITION, METHOD FOR OBTAINING SAME AND USE FOR COLOURING THE SKIN AND/OR KERATINOUS FIBRES | L"OREAL (FR) | 2002-04-18 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030103917-A1 | Dyeing composition promoting natural pigmentation, method for obtaining same and use for colouring the skin and/or keratinous fibres | TYR, KRT18, POLR1C | TNF 3893/4885RIPK1 4760/4885TYR 1/4885 |
| US-20030163878-A1 | Dyeing composition, method for obtaining the same and use for colouring the skin and/or keratinous fibres | KRT18, HAO2, TYR | TNF 3457/4885RIPK1 4513/4885TYR 3/4885 |
| US-20100005599-A1 | COMPOSITION FOR COLORING A KERATIN MATERIAL, COMPRISING AT LEAST TWO COMPONENTS, AND COLORING PROCESSES | KRT18, KATNA1, MARK1 | TNF 4748/4885RIPK1 4366/4885TYR 12/4885 |
| US-20020124330-A1 | Coloration composition, process for obtaining the same and its use for the coloration of keratin fibres | KRT18, TYR, OAT | TNF 4715/4885RIPK1 4752/4885TYR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.