Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.68 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6416042 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| Hydrochloric Acid SCHEMBL4624706 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL2608068 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL31686813 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL19652437 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL19652439 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL10072332 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| Bromide SCHEMBL28427490 | 0.97 | EPHX2 (0.68) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL15250808 | 0.96 | EPHX2 (0.65) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL10072334 | 0.93 | EPHX2 (0.59) | EPHX2SLC6A5KDM4ELPAR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1249488-B1 | Softener composition | KAO CORP (JP) | 2008-05-14 | — | — | EP | disclosed |
| US-7189687-B2 | Softener composition | KAO CORPORATION (JP) | 2007-03-13 | — | — | US | disclosed |
| US-20050090423-A1 | Softener composition | KAO CORPORATION | 2005-04-28 | — | — | US | disclosed |
| EP-1264874-B1 | Softener composition | KAO CORP (JP) | 2005-03-02 | — | — | EP | disclosed |
| US-6838427-B2 | For fabrics, imparts high softening regardless of the state of the rinsing water; specified mole ratio of 2 types of optionally ester or amide-functional tertiary amines or their ammonium salts and a sulfonate or sulfate anionic surfactant | KAO CORPORATION (JP) | 2005-01-04 | — | — | US | disclosed |
| US-6770617-B2 | (A) A COMPOUND WITH AN AMINO OR A QUATERNARY AMMONIUM GROUP AND A C8-36 HYDROCARBON GROUP; AND (B) A SULFONATE OR SULFATE ANIONIC SURFACTANT HAVING A C14-36 HYDROCARBON GROUP | KAO CORPORATION (JP) | 2004-08-03 | — | — | US | disclosed |
| US-20030060389-A1 | Softener composition | KAO CORPORATION (JP) | 2003-03-27 | — | — | US | disclosed |
| US-20020198129-A1 | Softener composition | KAO CORPORATION (JP) | 2002-12-26 | — | — | US | disclosed |
| EP-1264874-A1 | Softener composition | Kao Corporation (JP) | 2002-12-11 | — | — | EP | disclosed |
| EP-1249488-A1 | Softener composition | Kao Corporation (JP) | 2002-10-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090423-A1 | Softener composition | C1R, H1-10, C1S | EPHX2 513/4885SLC6A5 3250/4885KDM4E 3357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.