Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.68 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.63 |
| ▸ | CNR1 | P21554 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | HPGD | P15428 | 2/20 | 0.62 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4624712 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| Hydrochloric Acid SCHEMBL4624706 | 1.00 | EPHX2 (0.68) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL2608068 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL31686813 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL19652437 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL19652439 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL10072332 | 0.99 | EPHX2 (0.69) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| Bromide SCHEMBL28427490 | 0.97 | EPHX2 (0.68) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL15250808 | 0.96 | EPHX2 (0.65) | EPHX2SLC6A5KDM4ELPAR1CNR1 | |
| SCHEMBL10072334 | 0.93 | EPHX2 (0.59) | EPHX2SLC6A5KDM4ELPAR1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656277-B | Method for manufacturing environment-friendly pressureless sintering boron carbide ceramic material | 南通三责精密陶瓷有限公司 | 2022-12-27 | — | — | CN | claimed |
| CN-114538929-B | Preparation method of high-density boron carbide ceramic | 南通三责精密陶瓷有限公司 | 2022-11-18 | — | — | CN | claimed |
| CN-114656277-A | Method for manufacturing environment-friendly pressureless sintering boron carbide ceramic material | 南通三责精密陶瓷有限公司 | 2022-06-24 | — | — | CN | claimed |
| CN-114538929-A | Preparation method of high-density boron carbide ceramic | 南通三责精密陶瓷有限公司 | 2022-05-27 | — | — | CN | claimed |
| US-20250019587-A1 | SURFACTANT COMPOSITION | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2025-01-16 | — | — | US | disclosed |
| WO-2023094434-A1 | SURFACTANT COMPOSITION | NOURYON CHEMICALS INTERNATIONAL B.V. (NL) | 2023-06-01 | — | — | WO | disclosed |
| CN-114656277-B | Method for manufacturing environment-friendly pressureless sintering boron carbide ceramic material | 南通三责精密陶瓷有限公司 | 2022-12-27 | — | — | CN | disclosed |
| CN-114538929-B | Preparation method of high-density boron carbide ceramic | 南通三责精密陶瓷有限公司 | 2022-11-18 | — | — | CN | disclosed |
| CN-114656277-A | Method for manufacturing environment-friendly pressureless sintering boron carbide ceramic material | 南通三责精密陶瓷有限公司 | 2022-06-24 | — | — | CN | disclosed |
| CN-114538929-A | Preparation method of high-density boron carbide ceramic | 南通三责精密陶瓷有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-111040252-B | Modified calcium carbonate and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2021-08-03 | — | — | CN | disclosed |
| CN-111431498-A | Conductive polymer solution for crystal resonator and application thereof | 中国科学院宁波材料技术与工程研究所 | 2020-07-17 | — | — | CN | disclosed |
| CN-111234796-A | Surfactant and preparation method thereof | 中国石油天然气股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-111234796-A | Surfactant and preparation method thereof | 中国石油天然气股份有限公司 | 2020-06-05 | — | — | CN | disclosed |
| CN-111040252-A | Modified calcium carbonate and preparation method and application thereof | 中国科学院宁波材料技术与工程研究所 | 2020-04-21 | — | — | CN | disclosed |
| US-6964940-B1 | Method of preparing quaternized amidoamine surfactants | NALCO ENERGY SERVICES, L.P. (US) | 2005-11-15 | — | — | US | disclosed |