Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 11/20 | 0.51 |
| ▸ | ITGAV | P06756 | 1/20 | 0.51 |
| ▸ | ITGA4 | P13612 | 11/20 | 0.41 |
| ▸ | ITGB7 | P26010 | 8/20 | 0.37 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | GHSR | Q92847 | 1/20 | 0.34 |
| ▸ | PDCD1LG2 | Q9BQ51 | 1/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3319930 | 0.91 | ITGB1 (0.61) | ITGB1ITGAVITGA4ITGB7LMNA | |
| SCHEMBL4625005 | 0.86 | ITGB1 (0.40) | ITGB1ITGAVITGA4ITGB7MAPT | |
| SCHEMBL1028112 | 0.85 | ITGB1 (0.55) | ITGB1ITGAVITGA4ITGB7LMNA | |
| SCHEMBL4624059 | 0.85 | ITGA4 (0.50) | ITGB1ITGA4ITGB7FABP4LMNA | |
| SCHEMBL1030228 | 0.81 | ITGB1 (0.49) | ITGB1ITGAVLMNAHPGDMAPT | |
| SCHEMBL3313216 | 0.81 | ITGB1 (0.50) | ITGB1ITGAVITGA4ITGB7LMNA | |
| SCHEMBL6142440 | 0.80 | ITGB1 (0.42) | ITGB1ITGAVITGA4ITGB7LMNA | |
| SCHEMBL4625490 | 0.80 | ITGB1 (0.59) | ITGB1ITGAVITGA4ITGB7HPGD | |
| SCHEMBL3318793 | 0.79 | ITGB1 (0.81) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3314866 | 0.79 | ITGB1 (0.81) | ITGB1ITGAVITGA4ITGB7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501801-B1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF VLA-4 DEPENDENT DISEASES | UCB PHARMA SA (BE) | 2008-01-23 | — | — | EP | disclosed |