Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 4/20 | 0.40 |
| ▸ | ITGAV | P06756 | 1/20 | 0.40 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PTGFR | P43088 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CASR | P41180 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6142440 | 0.89 | ITGB1 (0.42) | ITGB1ITGAVITGA4ITGB7ALDH1A1 | |
| SCHEMBL4624872 | 0.86 | ITGB1 (0.51) | ITGB1ITGAVITGA4ITGB7MAPT | |
| SCHEMBL4624059 | 0.80 | ITGA4 (0.50) | ITGB1ITGA4ITGB7ALDH1A1SMN1; SMN2 | |
| SCHEMBL4626488 | 0.80 | ITGB1 (0.64) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3319930 | 0.80 | ITGB1 (0.61) | ITGB1ITGAVITGA4KMT2AITGB7 | |
| SCHEMBL4624998 | 0.78 | ITGB1 (0.54) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL1028112 | 0.75 | ITGB1 (0.55) | ITGB1ITGAVITGA4KMT2AITGB7 | |
| SCHEMBL4625003 | 0.73 | SMN1; SMN2 (0.41) | ITGB1ITGAVITGA4MEN1KMT2A | |
| SCHEMBL4624246 | 0.73 | ITGB1 (0.64) | ITGB1ITGAVITGA4ITGB7 | |
| SCHEMBL3313216 | 0.71 | ITGB1 (0.50) | ITGB1ITGAVITGA4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1501801-B1 | 2,6-QUINOLINYL AND 2,6-NAPHTHYL DERIVATIVES AND THEIR USE IN THE TREATMENT OF VLA-4 DEPENDENT DISEASES | UCB PHARMA SA (BE) | 2008-01-23 | — | — | EP | disclosed |