Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 8/20 | 0.65 |
| ▸ | BCHE | P06276 | 3/20 | 0.65 |
| ▸ | TGM2 | P21980 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | ALDH3A1 | P30838 | 5/20 | 0.57 |
| ▸ | ALDH2 | P05091 | 3/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | CDC25A | P30304 | 1/20 | 0.55 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4205713 | 0.83 | DRD2 (0.72) | CES1BCHETGM2ALDH1A1ALDH3A1 | |
| SCHEMBL4610945 | 0.83 | CES1 (0.61) | CES1BCHETGM2ALDH1A1ALDH3A1 | |
| Hydrochloric Acid SCHEMBL9397346 | 0.81 | DRD2 (0.70) | CES1BCHETGM2ALDH1A1ALDH3A1 | |
| SCHEMBL29649695 | 0.79 | CES1 (0.71) | CES1BCHETGM2ALDH1A1ALDH3A1 | |
| SCHEMBL5114051 | 0.79 | CES1 (0.71) | CES1BCHETGM2ALDH1A1ALDH3A1 | |
| SCHEMBL26930330 | 0.79 | TGM2 (1.00) | CES1BCHETGM2ALDH1A1ALDH3A1 | |
| SCHEMBL19924204 | 0.79 | CES1 (1.00) | CES1BCHETGM2ALDH1A1ALDH3A1 | |
| SCHEMBL3275917 | 0.79 | DRD3 (0.61) | CYP1A2HIF1AALDH1A1MAOB | |
| Ammonia Solution, Strong SCHEMBL27875488 | 0.78 | CES1 (0.69) | CES1BCHETGM2ALDH1A1ALDH3A1 | |
| SCHEMBL4625594 | 0.77 | CES1 (0.57) | CES1BCHETGM2ALDH1A1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | claimed |
| EP-1432428-B1 | Agent for colouring fibres containing keratin | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | claimed |
| EP-1705227-A2 | New dyestuffs and colorants with specific carbonyl compounds | Henkel Kommanditgesellschaft auf Aktien (DE) | 2006-09-27 | — | — | EP | claimed |
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2005-12-01 | — | — | US | claimed |
| EP-1575539-A1 | DYE TABLETS | Henkel Kommanditgesellschaft auf Aktien (DE) | 2005-09-21 | — | — | EP | claimed |
| EP-0977545-B1 | THE USE OF 1-SUBSTITUTED ISATINS TO DYE FIBERS CONTAINING KERATIN | HENKEL KGAA (DE) | 2005-02-16 | — | — | EP | claimed |
| WO-2004058202-A1 | DYE TABLETS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-07-15 | — | — | WO | claimed |
| EP-1434552-A1 | METHOD FOR DYEING KERATINOUS FIBRES | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-07-07 | — | — | EP | claimed |
| EP-1432428-A1 | Agent for colouring fibres containing keratin | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| WO-2003030841-A1 | METHOD FOR DYEING KERATINOUS FIBRES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| WO-2003030842-A1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | claimed |
| EP-1300133-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| EP-1300132-A2 | Agent for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2003-04-09 | — | — | EP | claimed |
| US-6203579-B1 | MIXTURE OF ISATIN DERIVATIVE AND AMINO COMPOUND | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-03-20 | — | — | US | claimed |
| EP-0977545-A1 | THE USE OF 1-SUBSTITUTED ISATINS TO DYE FIBERS CONTAINING KERATIN | Henkel Kommanditgesellschaft auf Aktien (DE) | 2000-02-09 | — | — | EP | claimed |
| WO-1998047472-A1 | THE USE OF 1-SUBSTITUTED ISATINS TO DYE FIBERS CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-10-29 | — | — | WO | claimed |
| EP-1432388-B1 | AGENT FOR COLOURING FIBRES CONTAINING KERATIN | HENKEL AG & CO KGAA (DE) | 2008-06-18 | — | — | EP | disclosed |
| EP-1432428-B1 | Agent for colouring fibres containing keratin | HENKEL KGAA (DE) | 2006-11-02 | — | — | EP | disclosed |
| WO-1998047472-A1 | THE USE OF 1-SUBSTITUTED ISATINS TO DYE FIBERS CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-10-29 | — | — | WO | disclosed |
| EP-0873745-A2 | Dyestuff for keratinous fibers | Henkel Kommanditgesellschaft auf Aktien (DE) | 1998-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050262647-A1 | Agent for dyeing fibers containing keratin | KRT18, CKAP4, KRTCAP2 | CES1 2379/4885BCHE 977/4885TGM2 1412/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.