Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17730533 | 0.79 | TSHR (0.40) | HSD17B10KDM4EALDH1A1 | |
| SCHEMBL4879037 | 0.78 | L3MBTL1 (0.33) | KDM4E | |
| SCHEMBL14822491 | 0.77 | KDM4E (0.45) | KDM4E | |
| SCHEMBL1864417 | 0.74 | HCAR2 (0.35) | KDM4E | |
| SCHEMBL4650593 | 0.74 | — | — | |
| SCHEMBL29129807 | 0.74 | GLRA3 (0.32) | KDM4E | |
| SCHEMBL28359144 | 0.73 | HCAR2 (0.35) | KDM4E | |
| SCHEMBL9211802 | 0.73 | HCAR2 (0.34) | KDM4E | |
| SCHEMBL3451427 | 0.73 | HCAR2 (0.49) | KDM4E | |
| SCHEMBL2466657 | 0.73 | CCNE2 (0.40) | HTTKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1067121-B1 | 5-Aminopyrazole-4-carboxylate derivative and process for preparing the same | MITSUI CHEMICALS INC (JP) | 2008-05-28 | — | — | EP | disclosed |
| US-6235911-B1 | 5-aminopyrazole-4-carboxylate derivative and process for preparing the same | MITSUI CHEMICALS, INC. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-1067121-A2 | 5-Aminopyrazole-4-carboxylate derivative and process for preparing the same | Mitsui Chemicals, Inc. (JP) | 2001-01-10 | — | — | EP | disclosed |