SCHEMBL9211802

SCHEMBL9211802

O=C(O)c1c(C(F)(F)F)n[nH]c1CCl

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 4/20 0.34
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9216975 0.88 HCAR2 (0.33) HCAR2KDM4EPOLBMAPTKMT2A
SCHEMBL8803433 0.87 HCAR2 (0.36) HCAR2
SCHEMBL1864417 0.84 HCAR2 (0.35) HCAR2KDM4EPOLBMAPTKMT2A
SCHEMBL3451427 0.83 HCAR2 (0.49) HCAR2KDM4EPOLBMAPTKMT2A
SCHEMBL9115479 0.79 HCAR2 (0.55) HCAR2KDM4EPOLBMAPTKMT2A
SCHEMBL9218976 0.74 HCAR2 (0.38) HCAR2KDM4EPOLBMAPTKMT2A
SCHEMBL4879037 0.74 L3MBTL1 (0.33) KDM4EPOLBMAPTKMT2A
SCHEMBL4625124 0.73 HSD17B10 (0.35) KDM4E
SCHEMBL14822491 0.73 KDM4E (0.45) HCAR2KDM4EPOLBMAPTKMT2A
SCHEMBL8803258 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0644879-A1 HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES RHONE POULENC AGRICULTURE LTD. (GB) 1995-03-29 EP disclosed